Evidence map›Paper›PMID 25987904›Full record

ArticleDiabetology & metabolic syndrome2015

Persistent organic pollutants as risk factors for type 2 diabetes.

Elvis Ndonwi Ngwa, Andre-Pascal Kengne, Barbara Tiedeu-Atogho, Edith-Pascale Mofo-Mato, Eugene Sobngwi

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02589756 (Fish or Nuts? Dietary Effects on Cardiometabolic Risk Factors and Persistent Organic Pollutants), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02589756 nacompletednot on this map

Fish or Nuts? Dietary Effects on Cardiometabolic Risk Factors and Persistent Organic Pollutants

TypeinterventionalSponsorOslo University HospitalRan2015 to 2017Enrolled120ConditionsObesity, Metabolic Syndrome, DiabetesArmsThe fatty fish group, The nut group, The control group
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Organic Pollutants and Risk of Type 2 Diabetes: A Systematic Review and Meta-analysis.Mayo Clinic proceedings. Innovations, quality & outcomes · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Critical Overview on Endocrine Disruptors in Diabetes Mellitus.International journal of molecular sciences · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. A review of AirQ Models and their applications for forecasting the air pollution health outcomes.Environmental science and pollution research international · 2017
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elvis Ndonwi NgwaLaboratory of Molecular Medicine and Metabolism, Biotechnology Centre Nkolbisson, Biotechnology Centre Nkolbisson, Yaounde, Cameroon.
Andre-Pascal KengneNon-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa ; Department of Medicine, University of Cape Town, Cape Town, South Africa.
Barbara Tiedeu-AtoghoLaboratory of Molecular Medicine and Metabolism, Biotechnology Centre Nkolbisson, Biotechnology Centre Nkolbisson, Yaounde, Cameroon.
Edith-Pascale Mofo-MatoLaboratory of Molecular Medicine and Metabolism, Biotechnology Centre Nkolbisson, Biotechnology Centre Nkolbisson, Yaounde, Cameroon.
Eugene SobngwiLaboratory of Molecular Medicine and Metabolism, Biotechnology Centre Nkolbisson, Biotechnology Centre Nkolbisson, Yaounde, Cameroon ; Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon ; National Obesity Center, Yaoundé Central Hospital and Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, P.O. Box 7535, Yaoundé, Cameroon.
South African Medical Research Council · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM) is a major and fast growing public health problem. Although obesity is considered to be the main driver of the pandemic of T2DM, a possible contribution of some environmental contaminants, of which persistent organic pollutants (POPs) form a particular class, has been suggested. POPs are organic compounds that are resistant to environmental degradation through chemical, biological, and photolytic processes which enable them to persist in the environment, to be capable of long-range transport, bio accumulate in human and animal tissue, bio accumulate in food chains, and to have potential significant impacts on human health and the environment. Several epidemiological studies have reported an association between persistent organic pollutants and diabetes risk. These findings have been replicated in experimental studies both in human (in-vitro) and animals (in-vivo and in-vitro), and patho-physiological derangements through which these pollutants exercise their harmful effect on diabetes risk postulated. This review summarizes available studies, emphasises on limitations so as to enable subsequent studies to be centralized on possible pathways and bring out clearly the role of POPs on diabetes risk.

Indexed as

Insulin resistanceInsulin secretionIn utero exposurePersistent organic pollutantsType 2 diabetes

Identifiers

PMID25987904
PMCPMC4435855
OpenAlexW2146173076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.