Evidence map›Paper›PMID 25987777›Full record

ArticleWorld journal of gastroenterology2015

Comparison of the diagnostic yield and outcomes between standard 8 h capsule endoscopy and the new 12 h capsule endoscopy for investigating small bowel pathology.

Merajur Rahman, Stuart Akerman, Bethany DeVito, Larry Miller, Meredith Akerman, Keith Sultan

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Gastrointestinal diagnosis using non-white light imaging capsule endoscopy.Nature reviews. Gastroenterology & hepatology · 2019
    Review
  5. No significant difference in clinically relevant findings between PillcamWorld journal of gastrointestinal endoscopy · 2019
    Article
  6. Article
  7. What defines quality in small bowel capsule endoscopy.Annals of translational medicine · 2018
    Review
  8. Review
  9. Contraindications for video capsule endoscopy.World journal of gastroenterology · 2016
    Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Merajur RahmanMerajur Rahman, Bethany DeVito, Larry Miller, Keith Sultan, Division of Gastroenterology, Department of Medicine, North Shore-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
Stuart AkermanMerajur Rahman, Bethany DeVito, Larry Miller, Keith Sultan, Division of Gastroenterology, Department of Medicine, North Shore-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
Bethany DeVitoMerajur Rahman, Bethany DeVito, Larry Miller, Keith Sultan, Division of Gastroenterology, Department of Medicine, North Shore-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
Larry MillerMerajur Rahman, Bethany DeVito, Larry Miller, Keith Sultan, Division of Gastroenterology, Department of Medicine, North Shore-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
Meredith AkermanMerajur Rahman, Bethany DeVito, Larry Miller, Keith Sultan, Division of Gastroenterology, Department of Medicine, North Shore-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
Keith SultanMerajur Rahman, Bethany DeVito, Larry Miller, Keith Sultan, Division of Gastroenterology, Department of Medicine, North Shore-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the completion rate and diagnostic yield of the PillCam SB2-ex in comparison to the PillCam SB2.

methodsTwo hundred cases using the 8-h PillCam SB2 were retrospectively compared to 200 cases using the 12 h PillCam SB2-ex at a tertiary academic center. Endoscopically placed capsules were excluded from the study. Demographic information, indications for capsule endoscopy, capsule type, study length, completion of exam, clinically significant findings, timestamp of most distant finding, and significant findings beyond 8 h were recorded.

resultsThe 8 and 12 h capsule groups were well matched respectively for both age (70.90 ± 14.19 vs 71.93 ± 13.80, P = 0.46) and gender (45.5% vs 48% male, P = 0.69). The most common indications for the procedure in both groups were anemia and obscure gastrointestinal bleeding. PillCam SB2-ex had a significantly higher completion rate than PillCam SB2 (88% vs 79.5%, P = 0.03). Overall, the diagnostic yield was greater for the 8 h capsule (48.5% for SB2 vs 35% for SB2-ex, P = 0.01). In 4/70 (5.7%) of abnormal SB2-ex exams the clinically significant finding was noted in the small bowel beyond the 8 h mark.

conclusionIn our study, we found the PillCam SB2-ex to have a significantly increased completion rate, though without any improvement in diagnostic yield compared to the PillCam SB2.

Indexed as

Capsule EndoscopyAgedAged, 80 and overAnemiaEndoscopesEquipment DesignFemaleGastrointestinal HemorrhageHumansIntestinal DiseasesIntestine, SmallMaleMiddle AgedNew YorkPredictive Value of TestsPrognosisCapsule endoscopyObscure gastrointestinal bleedingPillCam SB2

Identifiers

PMID25987777
PMCPMC4427676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.