ArticleChemical senses2015
Normal Taste Acceptance and Preference of PANX1 Knockout Mice.
Article in Chemical senses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Article
- Biology, function and structure of the calcium homeostasis modulator family.The Journal of physiology · 2025Review
- Sweet Taste Signaling: The Core Pathways and Regulatory Mechanisms.International journal of molecular sciences · 2022Review
- Purinergic neurotransmission in the gustatory system.Autonomic neuroscience : basic & clinical · 2021Article
- Article
- Taste transduction and channel synapses in taste buds.Pflugers Archiv : European journal of physiology · 2021Review
- Peripheral and central mechanisms of cough hypersensitivity.Journal of thoracic disease · 2020Review
- Single and population coding of taste in the gustatory cortex of awake mice.Journal of neurophysiology · 2019Article
- Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury.Frontiers in molecular neuroscience · 2019Article
- Altered salt taste response and increased tongue epithelium Scnna1 expression in adult Engrailed-2 null mice.Physiology & behavior · 2018Article
- CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes.Neuron · 2018Article
- ATP Release Channels.International journal of molecular sciences · 2018Review
- Taste buds: cells, signals and synapses.Nature reviews. Neuroscience · 2017Review
- WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation.Nature communications · 2017Article
- The Taste of Caffeine.Journal of caffeine research · 2017Review
- Action potentials and ion conductances in wild-type and CALHM1-knockout type II taste cells.Journal of neurophysiology · 2017Article
- Measurement of Behavioral Taste Responses in Mice: Two-Bottle Preference, Lickometer, and Conditioned Taste-Aversion Tests.Current protocols in mouse biology · 2016Article
- Calcium homeostasis modulator (CALHM) ion channels.Pflugers Archiv : European journal of physiology · 2016Review
- Mice Lacking Pannexin 1 Release ATP and Respond Normally to All Taste Qualities.Chemical senses · 2015Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Taste compounds detected by G protein-coupled receptors on the apical surface of Type 2 taste cells initiate an intracellular molecular cascade culminating in the release of ATP. It has been suggested that this ATP release is accomplished by pannexin 1 (PANX1). However, we report here that PANX1 knockout mice do not differ from wild-type controls in response to representative taste solutions, measured using 5-s brief-access tests or 48-h two-bottle choice tests. This implies that PANX1 is unnecessary for taste detection and consequently that ATP release from Type 2 taste cells does not require PANX1.
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