Evidence map›Paper›PMID 25987480›Full record

ReviewInfection2015

Ageing with HIV: a multidisciplinary review.

A Calcagno, S Nozza, C Muss, B M Celesia, F Carli, S Piconi, G V De Socio, A M Cattelan, G Orofino, D Ripamonti and 2 more

Erratum issuedOpen access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Aging with HIV: Increased Risk of HIV Comorbidities in Older Adults.International journal of environmental research and public health · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Prevalence and Correlates of Self-Rated Successful Aging Among Older Women Living With HIV.Journal of acquired immune deficiency syndromes (1999) · 2019
    Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

A CalcagnoUnit of Infectious Diseases, Department of Medical Sciences, University of Torino, Torino, Italy. andrea.calcagno@unito.it.
S NozzaDepartment of Infectious Diseases, San Raffaele Scientific Institute, Milano, Italy.
C MussCentro di Valutazione e Ricerca Gerontologica, University of Modena and Reggio Emilia, Modena, Italy.
B M CelesiaDivision of Infectious Diseases, Department of Clinical and Molecular Biomedicine, University of Catania, ARNAS Garibaldi, Catania, Italy.
F CarliDepartment of Mother, Child and Adult Medicine and Surgical Science, Infectious Diseases Clinic, University of Modena and Reggio Emilia, Modena, Italy.
S Piconi1st Division of Infectious Diseases Unit, University of Milano, Ospedale L. Sacco, Milano, Italy.
G V De SocioDepartment of Infectious Diseases, Azienda Ospedaliero-Universitaria di Perugia, Perugia, Italy.
A M CattelanUnit of Infectious Diseases, Department of Internal Medicine, Azienda Ospedaliera-Universitaria di Padova, Padova, Italy.
G OrofinoUnit of Infectious Diseases, "Divisione A", Ospedale Amedeo di Savoia, ASLTO2, Torino, Italy.
D RipamontiInfectious Diseases Unit, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy.
A Riva3rd Division of Infectious Diseases, University of Milano, Ospedale L. Sacco, Milano, Italy.
G Di PerriUnit of Infectious Diseases, Department of Medical Sciences, University of Torino, Torino, Italy.
University of Milan · ITUniversity of Modena and Reggio Emilia · ITUniversity of Turin · ITAzienda Ospedaliera di Padova · ITAzienda Ospedaliera di Perugia · ITOspedale Amedeo di Savoia · ITOspedale Papa Giovanni XXIII · ITSan Raffaele University of Rome · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAfter the introduction of highly active antiretroviral treatment, the course of HIV infection turned into a chronic disease and most of HIV-positive patients will soon be over 50 years old. MATERIAL AND

methodsThis paper reviews the multiple aspects that physicians have to face while taking care of HIV-positive ageing patients including the definitions of frailty and the prevalence and risk factors of concomitant diseases. From a therapeutic point of view pharmacokinetic changes and antiretroviral-specific toxicities associated with ageing are discussed; finally therapeutic approaches to frailty are reviewed both in HIV-positive and negative patients. CONCLUSION AND DISCUSSION: We conclude by suggesting that the combined use of drugs with the least toxicity potential and the promotion of healthy behaviours (including appropriate nutrition and exercise) might be the best practice for ageing HIV-positive subjects.

Indexed as

AgingLife StyleAnti-Retroviral AgentsHIV InfectionsHumansAnti-Retroviral AgentsAgeingComorbiditiesFrailtyHIVImmune senescencePharmacokineticsToxicity

Identifiers

PMID25987480
OpenAlexW222427327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.