Evidence map›Paper›PMID 25987294›Full record

ReviewSystematic reviews2015

Towards core outcome set (COS) development: a follow-up descriptive survey of outcomes in Cochrane reviews.

Francesca Wuytack, Valerie Smith, Mike Clarke, Paula Williamson, Elizabeth Gargon

Abstract readReview
In one paragraph

Review in Systematic reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
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  12. Standardized Outcomes in Nephrology-Peritoneal Dialysis (SONG-PD): Study Protocol for Establishing a Core Outcome Set in PD.Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis
    Article
  13. Core outcome sets for research and clinical practice.Brazilian journal of physical therapy
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francesca WuytackSchool of Nursing & Midwifery, Trinity College Dublin, 24 D'Olier Street, Dublin 2, Ireland. wuytacf@tcd.ie.
Valerie SmithSchool of Nursing & Midwifery, Trinity College Dublin, 24 D'Olier Street, Dublin 2, Ireland. SMITHV1@tcd.ie.
Mike ClarkeAll-Ireland Hub for Trials Methodology Research, Queens University Belfast, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland, UK. m.clarke@qub.ac.uk.
Paula WilliamsonDepartment of Biostatistics, University of Liverpool, Crown Street, Liverpool, L69 3BX, UK. P.R.Williamson@liverpool.ac.uk.
Elizabeth GargonDepartment of Biostatistics, University of Liverpool, Crown Street, Liverpool, L69 3BX, UK. E.Gargon@liverpool.ac.uk.

Funding

Medical Research Council G0901530Medical Research Council MR/J004847/1
6 · The paper itself

Abstract

backgroundA core outcome set (COS) can address problems of outcome heterogeneity and outcome reporting bias in trials and systematic reviews, including Cochrane reviews, helping to reduce waste. One of the aims of the international Core Outcome Measures in Effectiveness Trials (COMET) Initiative is to link the development and use of COS with the outcomes specified and reported in Cochrane reviews, including the outcomes listed in the summary of findings (SoF) tables. As part of this work, an earlier exploratory survey of the outcomes of newly published 2007 and 2011 Cochrane reviews was performed. This survey examined the use of COS, the variety of specified outcomes, and outcome reporting in Cochrane reviews by Cochrane Review Group (CRG). To examine changes over time and to explore outcomes that were repeatedly specified over time in Cochrane reviews by CRG, we conducted a follow-up survey of outcomes in 2013 Cochrane reviews.

methodsA descriptive survey of outcomes in Cochrane reviews that were first published in 2013. Outcomes specified in the methods sections and reported in the results section of the Cochrane reviews were examined by CRG. We also explored the uptake of SoF tables, the number of outcomes included in these, and the quality of the evidence for the outcomes.

resultsAcross the 50 CRGs, 375 Cochrane reviews that included at least one study specified a total of 3142 outcomes. Of these outcomes, 32 % (1008) were not reported in the results section of these reviews. For 23 % (233) of these non-reported outcomes, we did not find any reason in the text of the review for this non-report. Fifty-seven percent (216/375) of reviews included a SoF table.

conclusionsThe proportion of specified outcomes that were reported in Cochrane reviews had increased in 2013 (68 %) compared to 2007 (61 %) and 2011 (65 %). Importantly, 2013 Cochrane reviews that did not report specified outcomes were twice as likely to provide an explanation for why the outcome was not reported. There has been an increased uptake of SoF tables in Cochrane reviews. Outcomes that were repeatedly specified in Cochrane reviews by CRG in 2007, 2011, and 2013 may assist COS development.

Indexed as

Outcome Assessment, Health CareSurveys and QuestionnairesFollow-Up StudiesHumans

Identifiers

PMID25987294
PMCPMC4489040

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.