Evidence map›Paper›PMID 25987162›Full record

ArticleSystematic reviews2015

Colorectal cancer among persons with HIV: protocol for a systematic review and meta-analysis.

Joseph Djiometio Nguemo, Tyler J O'Neill, Nancy Kou, Anne-Marie Tynan, Ayda Agha, Ann N Burchell, Tony Antoniou

Open access · goldAbstract read
In one paragraph

Article in Systematic reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Joseph Djiometio NguemoDepartment of Family and Community Medicine, St. Michael's Hospital, 410 Sherbourne Street - 4th Floor, Toronto, Ontario, M4X 1K2, Canada. NguemoDjiomJ@smh.ca.
Tyler J O'NeillOntario HIV Treatment Network, Toronto, Ontario, Canada. t.oneill@mail.utoronto.ca.
Nancy KouCentre for Research on Inner City Health, St. Michael's Hospital, Toronto, Ontario, Canada. KouY@smh.ca.
Anne-Marie TynanCentre for Research on Inner City Health, St. Michael's Hospital, Toronto, Ontario, Canada. Tynanma@smh.ca.
Ayda AghaCentre for Research on Inner City Health, St. Michael's Hospital, Toronto, Ontario, Canada. aghaa@smh.ca.
Ann N BurchellOntario HIV Treatment Network, Toronto, Ontario, Canada. aburchell@ohtn.on.ca.
Tony AntoniouDepartment of Family and Community Medicine, St. Michael's Hospital, 410 Sherbourne Street - 4th Floor, Toronto, Ontario, M4X 1K2, Canada. tantoniou@smh.ca.
St. Michael's Hospital · CAInstitute for Clinical Evaluative Sciences · CAOntario HIV Treatment Network · CAPublic Health Ontario · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

backgroundAs persons with HIV live longer, data regarding the epidemiology of colorectal cancer are required to optimize the long-term management of these patients. The purpose of this systematic review and meta-analysis is to synthesize evidence regarding the incidence of colorectal cancer in persons with HIV. METHODS/

designOur primary outcome is the standardized incidence ratio of colorectal cancer among persons with HIV relative to rates in persons not living with HIV. Our secondary objectives are to summarize the evidence for differences with respect to stage at diagnosis, site of disease, and mortality due to colorectal cancer. We will search electronic bibliographic databases from their inception date, as well as conference proceedings and reference lists of included articles. Two investigators will independently screen citations and full-text articles, conduct data abstraction, and appraise study quality. We will examine clinical, methodological, and statistical heterogeneity among studies prior to conducting meta-analysis. Random effects meta-analysis methods will be employed to estimate standardized incidence ratios. These data will inform the development of guidelines for colorectal cancer screening in persons with HIV. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42014013449.

Indexed as

Colorectal NeoplasmsHIV InfectionsHumansMeta-Analysis as TopicSystematic Reviews as Topic

Identifiers

PMID25987162
PMCPMC4489358
OpenAlexW2132045662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.