Evidence map›Paper›PMID 25986631›Full record

ReviewBiophysical journal2015

The Classification and Evolution of Enzyme Function.

Sergio Martínez Cuesta, Syed Asad Rahman, Nicholas Furnham, Janet M Thornton

Open access · bronzeAbstract readReview
In one paragraph

Review in Biophysical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 133 citations in OpenAlex.

  1. Article
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  10. Learnable Filters for Geometric Scattering Modules.IEEE transactions on signal processing : a publication of the IEEE Signal Processing Society · 2024
    Article
  11. Article
  12. Article
  13. Review
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  16. An informatic workflow for the enhanced annotation of excretory/secretory proteins ofComputational and structural biotechnology journal · 2023
    Article
  17. In Silico Analysis of the Dextransucrase Obtained FromBioinformatics and biology insights · 2023
    Article
  18. Review
  19. Xylanase Production byBiotech (Basel (Switzerland)) · 2022
    Article
  20. Innovation and tinkering in the evolution of oxidases.Protein science : a publication of the Protein Society · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sergio Martínez CuestaEuropean Molecular Biology Laboratory, European Bioinformatics Institute EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
Syed Asad RahmanEuropean Molecular Biology Laboratory, European Bioinformatics Institute EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
Nicholas FurnhamDepartment of Pathogen Molecular Biology, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Janet M ThorntonEuropean Molecular Biology Laboratory, European Bioinformatics Institute EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom. Electronic address: thornton@ebi.ac.uk.
European Bioinformatics Institute · GBUniversity of London · GBWellcome Trust · GB

Funding

Medical Research Council MR/K020420/1
6 · The paper itself

Abstract

Enzymes are the proteins responsible for the catalysis of life. Enzymes sharing a common ancestor as defined by sequence and structure similarity are grouped into families and superfamilies. The molecular function of enzymes is defined as their ability to catalyze biochemical reactions; it is manually classified by the Enzyme Commission and robust approaches to quantitatively compare catalytic reactions are just beginning to appear. Here, we present an overview of studies at the interface of the evolution and function of enzymes.

Indexed as

Evolution, MolecularEnzymesEnzymes

Identifiers

PMID25986631
PMCPMC4576142
OpenAlexW1700031861

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.