Trial reportClinical neuroradiology2017
Process of the Functional Reorganization of the Cortical Centers for Movement in GBM Patients: fMRI Study.
Trial report in Clinical neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Role of Functional Imaging Techniques to Assess Motor and Language Cortical Plasticity in Glioma Patients: A Systematic Review.Neural plasticity · 2019Pooled it
- Changes in Somatomotor Network Connectivity Differentiate Better Versus Worse Recovery of Hand Dexterity After Brain Tumor Surgery: A Cohort Study.Neural plasticity · 2026Article
- Alterations of gray matter volume and structural covariance network in unilateral frontal lobe low-grade gliomas.BMC medical imaging · 2025Article
- Article
- The Father of Wisdom: "The Influence of Surgical Experience on Overall Survival in Patients with Malignant Gliomas".Advances and technical standards in neurosurgery · 2024Article
- Brain imaging and morphological plasticity in glioblastoma: a literature review.Journal of medicine and life · 2023Review
- Hemispheric Asymmetry of the Hand Motor Representations in Patients with Highly Malignant Brain Tumors: Implications for Surgery and Clinical Practice.Brain sciences · 2022Article
- Contralesional Cortical and Network Features Associated with Preoperative Language Deficit in Glioma Patients.Cancers · 2022Article
- Presurgical predictors of early cognitive outcome after brain tumor resection in glioma patients.NeuroImage. Clinical · 2022Article
- Contralesional Sensorimotor Network Participates in Motor Functional Compensation in Glioma Patients.Frontiers in oncology · 2022Article
- Review
- Direct Evidence of Plasticity within Human Primary Motor and Somatosensory Cortices of Patients with Glioblastoma.Neural plasticity · 2020Observational
- Plasticity of the Primary Motor Cortex in Patients with Primary Brain Tumors.Neural plasticity · 2020Article
- Motor Functional Reorganization Is Triggered by Tumor Infiltration Into the Primary Motor Area and Repeated Surgery.Frontiers in human neuroscience · 2020Article
- What do we know about pre- and postoperative plasticity in patients with glioma? A review of neuroimaging and intraoperative mapping studies.NeuroImage. Clinical · 2020Review
- Diffusion Tensor Imaging Shows Corpus Callosum Differences between High-Grade Gliomas and Metastases.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2018Article
- Anatomic Location of Tumor Predicts the Accuracy of Motor Function Localization in Diffuse Lower-Grade Gliomas Involving the Hand Knob Area.AJNR. American journal of neuroradiology · 2017Article
- Article
- Neuroplasticity: Insights from Patients Harboring Gliomas.Neural plasticity · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to verify whether the functional reorganization of motor cortex is associated with the increase in the size of WHO type IV glioma lesion, that is, disease duration and development, and whether surgical treatment has an impact on cerebral plasticity.
methodsThe study included 16 patients with primary tumors of the brain located at the region of central sulcus. The clinical status of patients and tumor volume was determined. Functional magnetic resonance imaging examinations were performed before and 3 months after operation.
resultsThe activity of all cortical centers, both contralateral and ipsilateral, was observed in a group of small as well as large tumors. The intensity of activation and the number of activated clusters of small tumors were almost always higher as compared with the large tumors. The frequency of the activity of contralateral areas was similar during the first and the second examination. In the case of ipsilateral centers, the frequency of activation during the second examination was lower. Mean values of t-statistics during the first examination were higher than during the second examination. Supplementary motor area (SMAa) was the only center for which the mean values of activation intensity remained similar.
conclusionsSMAa seems to play the most important role in the processes of motor cortex plasticity in high-grade glioma patients. Surgery seems not having a significant influence on the pattern of functional reorganization of the cortical centers for movement. Identification of the individual patterns of the reorganization of motor centers plays an important role in clinical practice.
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