ReviewPharmacoEconomics2015
A Review of the Development and Application of Generic Multi-Attribute Utility Instruments for Paediatric Populations.
Review in PharmacoEconomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 13 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- Measurement Properties of the EQ-5D Instruments in Children and Adolescents: A Systematic Review.Applied health economics and health policy · 2025Pooled it
- How do Health State Values Differ When Respondents Consider Adults Versus Children Living in Those States? A Systematic Review.PharmacoEconomics · 2025Pooled it
- Evidence for investing in parenting interventions aiming to improve child health: a systematic review of economic evaluations.European child & adolescent psychiatry · 2024Pooled it
- Systematic Review of the Psychometric Performance of Generic Childhood Multi-attribute Utility Instruments.Applied health economics and health policy · 2023Pooled it
- Patient-reported outcome measures used to improve youth mental health services: a systematic review.Journal of patient-reported outcomes · 2023Pooled it
- Are We Agreed? Self- Versus Proxy-Reporting of Paediatric Health-Related Quality of Life (HRQoL) Using Generic Preference-Based Measures: A Systematic Review and Meta-Analysis.PharmacoEconomics · 2022Pooled it
- Systematic Review of Conceptual, Age, Measurement and Valuation Considerations for Generic Multidimensional Childhood Patient-Reported Outcome Measures.PharmacoEconomics · 2022Pooled it
- Health utilities in pediatric cancer patients and survivors: a systematic review and meta-analysis for clinical implementation.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Pooled it
- Dimensions Used in Instruments for QALY Calculation: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- A comparison of self-reported and proxy-reported health utilities in children: a systematic review and meta-analysis.Health and quality of life outcomes · 2021Pooled it
- A Systematic Review of the Use and Quality of Qualitative Methods in Concept Elicitation for Measures with Children and Young People.The patient · 2020Pooled it
- A systematic review of utility values in children with cerebral palsy.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Pooled it
- A review of preference-based measures for the assessment of quality of life in children and adolescents with cerebral palsy.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018Pooled it
- Intravenous versus oral antibiotics for eradication of Pseudomonas aeruginosa in cystic fibrosis (TORPEDO-CF): a randomised controlled trial.The Lancet. Respiratory medicine · 2020Trial
- Association of Adverse Childhood Experiences With Health-Related Quality of Life and Quality-Adjusted Life-Years Among Adolescents in the United Kingdom: Findings From Two General Population Cohorts.Alpha psychiatry · 2026Article
- Exploring the Sensitivity of Utilities Predicted by the EQ-5D, SF-6D, HUI3, 15D, AQoL-4D, and AQoL-8D Multi-Attribute Utility Instruments to SF-36 Dimensions.PharmacoEconomics - open · 2026Article
- Individual-level prediction models of societal costs and health-related quality of life in pediatric cerebral palsy: a population-based study from Spain.Cost effectiveness and resource allocation : C/E · 2026Article
- EQ-5D(-Y) Valuation from Adult and Child Perspectives: Where Does the Empirical Evidence Leave Us and How Should We Proceed?PharmacoEconomics · 2026Review
- Psychometric properties comparison of EQ-5D-Y-3L and CHU9D in children and adolescents across different BMI classifications in Jiangsu, China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Assessing well-being in younger populations in economic evaluations: a scoping review of multidimensional instruments.Health and quality of life outcomes · 2025Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multi-attribute utility instruments (MAUIs) are increasingly being used as a means of quantifying utility for the calculation of quality-adjusted life-years within the context of cost utility analysis. Traditionally, MAUIs have been developed and applied in adult populations. However, increasingly, researchers in health economics and other disciplines are recognising the importance of the measurement and valuation of health in both children and adolescents. Presently, there are nine generic MAUIs available internationally that have been used in paediatric populations: the Quality of Well-Being Scale (QWB), the Health Utility Index Mark 2 (HUI2), the HUI3, the Sixteen-dimensional measure of health-related quality of life (HRQoL) (16D), the Seventeen-dimensional measure of HRQoL (17D), the Assessment of Quality of Life 6-Dimension (AQoL-6D) Adolescent, the Child Health Utility 9D (CHU9D), the EQ-5D Youth version (EQ-5D-Y) and the Adolescent Health Utility Measure (AHUM). This paper critically reviews the development and application of the above nine MAUIs and discusses the specific challenges of health utility measurement in children and adolescents. Areas for further research relating to the development and application of generic MAUIs in paediatric populations are highlighted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.