Evidence map›Paper›PMID 25985922›Full record

ArticleJournal of psychiatric research

Structure and correlates of self-reported empathy in schizophrenia.

William P Horan, Steven P Reise, Robert S Kern, Junghee Lee, David L Penn, Michael F Green

Abstract read
In one paragraph

Article in Journal of psychiatric research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  12. Empathic Accuracy Task: Indian Adaptation and Validation.Indian journal of psychological medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William P HoranVA Greater Los Angeles Healthcare System, USA; Semel Institute for Neuroscience and Human Behavior, UCLA, USA. Electronic address: horan@ucla.edu.
Steven P ReiseDepartment of Psychology, UCLA, USA.
Robert S KernVA Greater Los Angeles Healthcare System, USA; Semel Institute for Neuroscience and Human Behavior, UCLA, USA.
Junghee LeeVA Greater Los Angeles Healthcare System, USA; Semel Institute for Neuroscience and Human Behavior, UCLA, USA.
David L PennUniversity of North Carolina, Chapel Hill, USA; Australian Catholic University, Melbourne, VI, Australia.
Michael F GreenVA Greater Los Angeles Healthcare System, USA; Semel Institute for Neuroscience and Human Behavior, UCLA, USA.

Funding

The Genetics of Endophenotypes and SchizophreniaR01MH065707 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GREEN, MICHAEL F. · 2003 to 2013
$3.6M
EARLY VISUAL PROCESSING IN SCHIZOPHRENIAR01MH043292 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GREEN, MICHAEL F. · 1996 to 2010
$3.5M
Social Cognition and Functioning in SchizophreniaR01MH087618 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GREEN, MICHAEL F. · 2010 to 2013
$1.5M
EARLY VISUAL PROCESSING IN SCHIZOPHRENIAR29MH043292 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GREEN, MICHAEL F · 1988 to 1992
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NIMH NIH HHS MH043292NIMH NIH HHS MH065707NIMH NIH HHS MH087618NIMH NIH HHS R01 MH043292NIMH NIH HHS R01 MH065707NIMH NIH HHS R01 MH087618NIMH NIH HHS R29 MH043292
6 · The paper itself

Abstract

Research on empathy in schizophrenia has relied on dated self-report scales that do not conform to contemporary social neuroscience models of empathy. The current study evaluated the structure and correlates of the recently-developed Questionnaire of Cognitive and Affective Empathy (QCAE) in schizophrenia. This measure, whose structure and validity was established in healthy individuals, includes separate scales to assess the two main components of empathy: Cognitive Empathy (assessed by two subscales) and Affective Empathy (assessed by three subscales). Stable outpatients with schizophrenia (n = 145) and healthy individuals (n = 45) completed the QCAE, alternative measures of empathy, and assessments of clinical symptoms, neurocognition, and functional outcome. Exploratory and confirmatory factor analyses provided consistent support for a two-factor solution in the schizophrenia group, justifying the use of separate cognitive and affective empathy scales in this population. However, one of the three Affective Empathy subscales was not psychometrically sound and was excluded from further analyses. Patients reported significantly lower Cognitive Empathy but higher Affective Empathy than controls. Among patients, the QCAE scales showed significant correlations with an alternative self-report empathy scale, but not with performance on an empathic accuracy task. The QCAE Cognitive Empathy subscales also showed significant, though modest, correlations with negative symptoms and functional outcome. These findings indicate that structure of self-reported empathy is similar in people with schizophrenia and healthy subjects, and can be meaningfully compared between groups. They also contribute to emerging evidence that some aspects of empathy may be intact or hyper-responsive in schizophrenia.

Indexed as

EmpathySchizophrenic PsychologyAdultCognitionFactor Analysis, StatisticalFemaleHumansMalePsychological TestsPsychometricsSchizophreniaSelf ReportEmpathyQCAESchizophreniaSocial cognitionSocial functioning

Identifiers

PMID25985922
PMCPMC4458171

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.