Evidence map›Paper›PMID 25984635›Full record

ArticlePsychological assessment2016

Trait-based assessment of borderline personality disorder using the NEO Five-Factor Inventory: Phenotypic and genetic support.

Lauren R Few, Joshua D Miller, Julia D Grant, Jessica Maples, Timothy J Trull, Elliot C Nelson, Thomas F Oltmanns, Nicholas G Martin, Michael T Lynskey, Arpana Agrawal

Erratum issuedOpen access · hybridAbstract readValidation Study
In one paragraph

Article in Psychological assessment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Self-report response style bias and borderline personality features.Current psychology (New Brunswick, N.J.) · 2023
    Article
  6. Article
  7. The Impact of Personality Pathology Across Three Generations: Evidence from the St. Louis Personality and Intergenerational Network Study.Clinical psychological science : a journal of the Association for Psychological Science · 2021
    Article
  8. Borderline Personality Traits Are Not Correlated With Brain Structure in Two Large Samples.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020
    Article
  9. Article
  10. Article
  11. Borderline Personality Disorder: Why 'fast and furious'?Evolution, medicine, and public health · 2016
    Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Lauren R FewDepartment of Psychiatry, Washington University School of Medicine.
Joshua D MillerDepartment of Psychology, University of Georgia.
Julia D GrantDepartment of Psychiatry, Washington University School of Medicine.
Jessica MaplesDepartment of Psychology, University of Georgia.
Timothy J TrullDepartment of Psychological Sciences, University of Missouri.
Elliot C NelsonDepartment of Psychiatry, Washington University School of Medicine.
Thomas F OltmannsDepartment of Psychology, Washington University.
Nicholas G MartinQIMR Medical Research Institute.ORCID 0000-0003-4069-8020
Michael T LynskeyInstitute of Psychiatry, Psychology & Neuroscience, King's College London.
Arpana AgrawalDepartment of Psychiatry, Washington University School of Medicine.
University of Georgia · USKing's College London · GBQIMR Berghofer Medical Research Institute · AUUniversity of Missouri · US

Funding

Personality, Health, and Transitions in Later LifeR01MH077840 · NIMH · WASHINGTON UNIVERSITY · PI OLTMANNS, THOMAS · 2007 to 2011
$2.6M
CANNABIS AND TOBACCO INVOLVEMENT: A TWIN STUDYR01DA023668 · NIDA · WASHINGTON UNIVERSITY · PI AGRAWAL, ARPANA · 2007 to 2016
$2.5M
Cannabis and Other Illicit Drug Use: A Twin StudyR01DA018267 · NIDA · WASHINGTON UNIVERSITY · PI LYNSKEY, MICHAEL THOMAS · 2005 to 2009
$2.4M
DELINEATING THE ROLE OF GENETIC INFLUENCES ON CANNABIS INVOLVEMENTK02DA032573 · NIDA · WASHINGTON UNIVERSITY · PI AGRAWAL, ARPANA · 2012 to 2021
$1.1M
Characterizing Affective Instability Using EMAR21MH069472 · NIMH · UNIVERSITY OF MISSOURI-COLUMBIA · PI TRULL, TIMOTHY J · 2004 to 2006
$539k
The Genetics of Co-occurring Alcohol Use and Self-HarmF32AA023693 · NIAAA · WASHINGTON UNIVERSITY · PI FEW, LAUREN RACHEL · 2014 to 2015
$97k
NIAAA NIH HHS AA023693NIAAA NIH HHS F32 AA023693NIDA NIH HHS DA18267NIDA NIH HHS DA23668NIDA NIH HHS DA32573NIDA NIH HHS K02 DA032573NIDA NIH HHS R01 DA018267NIDA NIH HHS R01 DA023668NIMH NIH HHS MH069472NIMH NIH HHS MH077840NIMH NIH HHS R01 MH077840NIMH NIH HHS R21 MH069472
6 · The paper itself

Abstract

[Correction Notice: An Erratum for this article was reported in Vol 28(1) of Psychological Assessment (see record 2015-54029-001). The FFI-BPD values for Sample 3 in Table 2 should read 1.42 (0.44), 0.83.] The aim of the current study was to examine the reliability and validity of a trait-based assessment of borderline personality disorder (BPD) using the NEO Five-Factor Inventory. Correlations between the Five-Factor Inventory-BPD composite (FFI-BPD) and explicit measures of BPD were examined across 6 samples, including undergraduate, community, and clinical samples. The median correlation was .60, which was nearly identical to the correlation between measures of BPD and a BPD composite generated from the full Revised NEO Personality Inventory (i.e., NEO-BPD; r = .61). Correlations between FFI-BPD and relevant measures of psychiatric symptomatology and etiology (e.g., childhood abuse, drug use, depression, and personality disorders) were also examined and compared to those generated using explicit measures of BPD and NEO-BPD. As expected, the FFI-BPD composite correlated most strongly with measures associated with high levels of Neuroticism, such as depression, anxiety, and emotion dysregulation, and the pattern of correlations generated using the FFI-BPD was highly similar to those generated using explicit measures of BPD and NEO-BPD. Finally, genetic analyses estimated that FFI-BPD is 44% heritable, which is comparable to meta-analytic research examining genetics associated with BPD, and revealed that 71% of the genetic influences are shared between FFI-BPD and a self-report measure assessing BPD (Personality Assessment Inventory-Borderline subscale; Morey, 1991). Generally, these results support the use of FFI-BPD as a reasonable proxy for BPD, which has considerable implications, particularly for potential gene-finding efforts in large, epidemiological datasets that include the NEO FFI.

Indexed as

Personality InventoryPsychiatric Status Rating ScalesAdultAgedBorderline Personality DisorderFemaleGenetic Predisposition to DiseaseHumansMaleMiddle AgedPhenotypePsychometricsReproducibility of Results

Identifiers

PMID25984635
PMCPMC4651858
OpenAlexW2394780812

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.