Evidence map›Paper›PMID 25984571›Full record

ReviewACS biomaterials science & engineering2015

Nanotherapy for Cancer: Targeting and Multifunctionality in the Future of Cancer Therapies.

Asiri Ediriwickrema, W Mark Saltzman

Abstract readReview
In one paragraph

Review in ACS biomaterials science & engineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed.

  1. Selenium-Containing Compounds in Breast Cancer Therapy.Biological trace element research · 2026
    Review
  2. Review
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  6. Review
  7. Article
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  9. A Nanorobotics-Based Approach of Breast Cancer in the Nanotechnology Era.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Review
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  13. Article
  14. Nano-inspired smart medicines targeting brain cancer: diagnosis and treatment.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023
    Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Asiri EdiriwickremaDepartment of Biomedical Engineering, Yale University , 55 Prospect Street, MEC 414, New Haven, Connecticut 06511, United States.
W Mark SaltzmanDepartment of Biomedical Engineering, Yale University , 55 Prospect Street, MEC 414, New Haven, Connecticut 06511, United States.

Funding

CED of Nanoparticles Loading with Novel Agents for Improved Treatment of GliomasR01CA149128 · NCI · YALE UNIVERSITY · PI SALTZMAN, W. MARK · 2011 to 2020
$3.5M
NCI NIH HHS R01 CA149128
6 · The paper itself

Abstract

Cancer continues to be a prevalent and lethal disease, despite advances in tumor biology research and chemotherapy development. Major obstacles in cancer treatment arise from tumor heterogeneity, drug resistance, and systemic toxicities. Nanoscale delivery systems, or nanotherapies, are increasing in importance as vehicles for antineoplastic agents because of their potential for targeting and multifunctionality. We discuss the current field of cancer therapy and potential strategies for addressing obstacles in cancer treatment with nanotherapies. Specifically, we review the strategies for rationally designing nanoparticles for targeted, multimodal delivery of therapeutic agents.

Indexed as

cancer therapydrug deliverygene deliverynanoparticle

Identifiers

PMID25984571
PMCPMC4426346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.