Evidence map›Paper›PMID 25984570›Full record

ArticleACS biomaterials science & engineering2015

3D Printing with Nucleic Acid Adhesives.

Peter B Allen, Zin Khaing, Christine E Schmidt, Andrew D Ellington

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS biomaterials science & engineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peter B AllenDepartmet of Chemistry and Biochemistry, University of Texas at Austin , 1 University Station, Austin, Texas, United States.
Zin KhaingDepartmet of Chemistry and Biochemistry, University of Texas at Austin , 1 University Station, Austin, Texas, United States.
Christine E SchmidtDepartmet of Chemistry and Biochemistry, University of Texas at Austin , 1 University Station, Austin, Texas, United States.
Andrew D EllingtonDepartmet of Chemistry and Biochemistry, University of Texas at Austin , 1 University Station, Austin, Texas, United States.

Funding

Amorphous computation with transcription logic gatesR01GM094933 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI ELLINGTON, ANDREW D · 2010 to 2013
$1.2M
NIGMS NIH HHS R01 GM094933
6 · The paper itself

Abstract

By relying on specific DNA:DNA interactions as a "smart glue", we have assembled microparticles into a colloidal gel that can hold its shape. This gel can be extruded with a 3D printer to generate centimeter size objects. We show four aspects of this material: (1) The colloidal gel material holds its shape after extrusion. (2) The connectivity among the particles is controlled by the binding behavior between the surface DNA and this mediates some control over the microscale structure. (3) The use of DNA-coated microparticles dramatically reduces the cost of DNA-mediated assembly relative to conventional DNA nanotechnologies and makes this material accessible for macroscale applications. (4) This material can be assembled under biofriendly conditions and can host growing cells within its matrix. The DNA-based control over organization should provide a new means of engineering bioprinted tissues.

Indexed as

3D printingcolloidal gelDNAhybridizationmicroparticlesself-assembly

Identifiers

PMID25984570
PMCPMC4426351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.