Evidence map›Paper›PMID 25984566›Full record

ArticleACS infectious diseases2015

Putting Tuberculosis (TB) To Rest: Transformation of the Sleep Aid, Ambien, and "Anagrams" Generated Potent Antituberculosis Agents.

Garrett C Moraski, Patricia A Miller, Mai Ann Bailey, Juliane Ollinger, Tanya Parish, Helena I Boshoff, Sanghyun Cho, Jeffery R Anderson, Surafel Mulugeta, Scott G Franzblau and 1 more

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 50 citations in OpenAlex.

  1. Imidazo[1,2‑ACS omega · 2026
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  2. Recent developments of imidazo[1,2-RSC medicinal chemistry · 2023
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  4. Targeting the cytochrome bcMolecular diversity · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Garrett C MoraskiDepartment of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame , Notre Dame, Indiana 46556, United States.
Patricia A MillerDepartment of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame , Notre Dame, Indiana 46556, United States.
Mai Ann BaileyTB Discovery Research, Infectious Disease Research Institute, 1616 Eastlake Avenue E, Suite 400, Seattle, Washington 98102, United States.
Juliane OllingerTB Discovery Research, Infectious Disease Research Institute, 1616 Eastlake Avenue E, Suite 400, Seattle, Washington 98102, United States.
Tanya ParishTB Discovery Research, Infectious Disease Research Institute, 1616 Eastlake Avenue E, Suite 400, Seattle, Washington 98102, United States.
Helena I BoshoffTuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Bethesda, Maryland 20892, United States.
Sanghyun ChoInstitute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago , 833 South Wood Street, Chicago, Illinois 60612, United States.
Jeffery R AndersonInstitute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago , 833 South Wood Street, Chicago, Illinois 60612, United States.
Surafel MulugetaInstitute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago , 833 South Wood Street, Chicago, Illinois 60612, United States.
Scott G FranzblauInstitute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago , 833 South Wood Street, Chicago, Illinois 60612, United States.
Marvin J MillerDepartment of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame , Notre Dame, Indiana 46556, United States.
University of Illinois Chicago · USInfectious Disease Research Institute · USUniversity of Notre Dame · USNational Institutes of Health · US

Funding

Development Of New Chemotherapeutics For TuberculosisZIAAI000693 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BARRY, CLIFTON · 2009 to 2025
$20.1M
Design/Syntheses/Studies/Novel Antituberculosis AgentsR01AI054193 · NIAID · UNIVERSITY OF NOTRE DAME · PI MILLER, MARVIN J · 2004 to 2014
$3.2M
NIAID NIH HHS R01 AI054193
6 · The paper itself

Abstract

Zolpidem (Ambien,

Indexed as

Ambienanti-TBimidazopyridine analoguestuberculosiszolpidem

Identifiers

PMID25984566
PMCPMC4426345
OpenAlexW1977386448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.