Evidence map›Paper›PMID 25984455›Full record

ArticleCardiovascular diagnosis and therapy2015

Non-identical yet similar: presentation of coronary artery disease in dizygotic twins.

Shivanand S Patil, Rangraj Ramalingam, Kasamshetty Subramanyam, Deepak Pujar, Cholenahally Nanjappa Manjunath, Nirlep Gajiwala, Ashok Thakkar

Open access · greenAbstract read
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shivanand S Patil1 Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore-560069, Karnataka, India ; 2 Department of Clinical Trials, Sahajanand Medical Technologies Pvt. Ltd., Surat-395004, Gujarat, India.
Rangraj Ramalingam1 Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore-560069, Karnataka, India ; 2 Department of Clinical Trials, Sahajanand Medical Technologies Pvt. Ltd., Surat-395004, Gujarat, India.
Kasamshetty Subramanyam1 Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore-560069, Karnataka, India ; 2 Department of Clinical Trials, Sahajanand Medical Technologies Pvt. Ltd., Surat-395004, Gujarat, India.
Deepak Pujar1 Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore-560069, Karnataka, India ; 2 Department of Clinical Trials, Sahajanand Medical Technologies Pvt. Ltd., Surat-395004, Gujarat, India.
Cholenahally Nanjappa Manjunath1 Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore-560069, Karnataka, India ; 2 Department of Clinical Trials, Sahajanand Medical Technologies Pvt. Ltd., Surat-395004, Gujarat, India.
Nirlep Gajiwala1 Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore-560069, Karnataka, India ; 2 Department of Clinical Trials, Sahajanand Medical Technologies Pvt. Ltd., Surat-395004, Gujarat, India.
Ashok Thakkar1 Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore-560069, Karnataka, India ; 2 Department of Clinical Trials, Sahajanand Medical Technologies Pvt. Ltd., Surat-395004, Gujarat, India.
SMT (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a considerable debate regarding the role of genetic and the environmental factors in the pathogenesis of coronary artery disease (CAD). Since twin pairs are exposed to similar prenatal and postnatal environmental factors, a particular role of genetic vs. environmental factors can be evaluated by investigating the twins. We report a case of a dizygotic twin-pair who presented with simultaneous development of coronary insufficiency, and underwent coronary angiography and stent implantation on the same day. There were striking similarities and differences in certain characteristics between the presenting twins. We believe that the occurrence of CAD might be predetermined genetically, while the location of CAD lesion and its severity might be subjected to the modification of environmental factors among dizygotic twins. Considering the high risk of CAD-related fatal events in monozygotic and dizygotic twins, we recommend aggressive medical surveillance for a twin individual, whose co-twin has reported a cardiac event.

Indexed as

Coronary angiographycoronary artery disease (CAD)dizygoticrisk factortwins

Identifiers

PMID25984455
PMCPMC4420676
OpenAlexW2204751639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.