Evidence map›Paper›PMID 25984377›Full record

ArticleCase reports in ophthalmological medicine2015

Clinical findings and genetic expression profiling of three pigmented lesions of the optic nerve.

Manuel A de Alba, Victor M Villegas, Aaron S Gold, Andrea Wildner, Fiona J Ehlies, Azeema Latiff, Timothy G Murray

Open access · goldAbstract read
In one paragraph

Article in Case reports in ophthalmological medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Manuel A de AlbaMurray Ocular Oncology and Retina, 6705 Red Road, Suite 412, Miami, FL 33143, USA.
Victor M VillegasMurray Ocular Oncology and Retina, 6705 Red Road, Suite 412, Miami, FL 33143, USA.
Aaron S GoldMurray Ocular Oncology and Retina, 6705 Red Road, Suite 412, Miami, FL 33143, USA.
Andrea WildnerMurray Ocular Oncology and Retina, 6705 Red Road, Suite 412, Miami, FL 33143, USA.
Fiona J EhliesMurray Ocular Oncology and Retina, 6705 Red Road, Suite 412, Miami, FL 33143, USA.
Azeema LatiffMurray Ocular Oncology and Retina, 6705 Red Road, Suite 412, Miami, FL 33143, USA.
Timothy G MurrayMurray Ocular Oncology and Retina, 6705 Red Road, Suite 412, Miami, FL 33143, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background. Optic disk melanocytoma is a primary tumor of the optic disk that represents a clinical diagnostic challenge due to its similarities with melanoma. Purpose. The authors present three cases in which genetic expression profiling was used to identify tumor prognosis of optic disk melanocytoma. Case Series. In two cases fine-needle aspiration biopsy was performed to obtain tissue through a transvitreal route into the apex of the tumor while the patient underwent pars plana vitrectomy, laser ablation, phacoemulsification with posterior chamber intraocular lens implantation, and intravitreal triamcinolone acetonide. In the other case the tissue was obtained after definite enucleation. Conclusion. Genetic expression profiling is a useful diagnostic tool for classification and can provide vital information to the ocular oncologist regarding prognosis.

Identifiers

PMID25984377
PMCPMC4423014
OpenAlexW2087836911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.