ReviewFrontiers in microbiology2015
Molecular epidemiology of Methicillin-resistant Staphylococcus aureus in Africa: a systematic review.
Review in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
93 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prevalence of methicillin-resistant coagulase-negative staphylococci in Africa: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Occurrence, multidrug resistance and potential risk factors forFrontiers in public health · 2024Pooled it
- Methicillin resistant Staphylococcus aureus in Ethiopia: a meta-analysis.BMC infectious diseases · 2016Pooled it
- Molecular characterization of PVL-positive methicillin-resistant Staphylococcus aureus (MRSA) isolates from skin and soft tissue infections in Alexandria, Egypt.Archives of microbiology · 2026Article
- Methicillin-ResistantInternational journal of molecular sciences · 2026Review
- Characterization and diversity of methicillin-resistant Staphylococcus aureus in two hospitals in Gabon.BMC infectious diseases · 2025Article
- Article
- Repurposing pinaverium bromide against Staphylococcus and its biofilms with new mechanisms.AMB Express · 2024Article
- Sequencing a CC239-MRSA-III with a novel composite SCC mec element from Kuwait.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024Article
- Genomic Characterization of Methicillin-Resistant and Methicillin-SusceptibleAntibiotics (Basel, Switzerland) · 2024Article
- Pathogenomic profile and clonal diversity of potential zoonotic MRSA-CC7-ST789-t091-SCCmecV from human skin and soft tissue infections.Scientific reports · 2024Article
- Methicillin-resistantJournal of medical microbiology · 2024Article
- Phenotypic and genotypic characterization of commensal staphylococci isolated from young volunteers in Alexandria, Egypt.Scientific reports · 2024Article
- Displacement of Hospital-Acquired, Methicillin-ResistantMicroorganisms · 2024Article
- Virulence attributes of successful methicillin-resistantClinical microbiology reviews · 2023Review
- Whole Genome Sequencing and Molecular Epidemiology of Clinical Isolates ofMicroorganisms · 2023Article
- Genomic Diversity of Methicillin-Resistant Staphylococcus aureus CC398 Isolates Collected from Diseased Swine in the German National Resistance Monitoring Program GEMicrobiology spectrum · 2023Article
- Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2023Article
- Molecular Characterization ofMicroorganisms · 2023Article
- Multidrug-Resistant Staphylococcus aureus Isolates in a Tertiary Care Hospital, Kingdom of Bahrain.Cureus · 2023Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) infections are a serious global problem, with considerable impact on patients and substantial health care costs. This systematic review provides an overview on the clonal diversity of MRSA, as well as the prevalence of Panton-Valentine leukocidin (PVL)-positive MRSA in Africa. A search on the molecular characterization of MRSA in Africa was conducted by two authors using predefined terms. We screened for articles published in English and French through to October 2014 from five electronic databases. A total of 57 eligible studies were identified. Thirty-four reports from 15 countries provided adequate genotyping data. CC5 is the predominant clonal complex in the healthcare setting in Africa. The hospital-associated MRSA ST239/ST241-III [3A] was identified in nine African countries. This clone was also described with SCCmec type IV [2B] in Algeria and Nigeria, and type V [5C] in Niger. In Africa, the European ST80-IV [2B] clone was limited to Algeria, Egypt and Tunisia. The clonal types ST22-IV [2B], ST36-II [2A], and ST612-IV [2B] were only reported in South Africa. No clear distinctions were observed between MRSA responsible for hospital and community infections. The community clones ST8-IV [2B] and ST88-IV [2B] were reported both in the hospital and community settings in Angola, Cameroon, Gabon, Ghana, Madagascar, Nigeria, and São Tomé and Príncipe. The proportion of PVL-positive MRSA carriage and/or infections ranged from 0.3 to 100% in humans. A number of pandemic clones were identified in Africa. Moreover, some MRSA clones are limited to specific countries or regions. We strongly advocate for more surveillance studies on MRSA in Africa.
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