Evidence map›Paper›PMID 25983688›Full record

ArticleFrontiers in human neuroscience2015

Prism adaptation and spatial neglect: the need for dose-finding studies.

Kelly M Goedert, Jeffrey Y Zhang, A M Barrett

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Kelly M GoedertDepartment of Psychology, Seton Hall University South Orange, NJ, USA.
Jeffrey Y ZhangPrinceton Pharmatech Princeton, NJ, USA.
A M BarrettStroke Rehabilitation Research, Kessler Foundation West Orange, NJ, USA ; Department of Neurology and Neurosciences, Rutgers-New Jersey Medical School Newark, NJ, USA ; Department of Physical Medicine and Rehabilitation, Rutgers-New Jersey Medical School Newark, NJ, USA.
Kessler Foundation · USPrinceton BioMeditech (United States) · USSeton Hall University · US

Funding

Building a science for treatment of spatial neglectR01NS055808 · NINDS · KESSLER FOUNDATION, INC. · PI BARRETT, A. M. · 2008 to 2011
$1.6M
Mentoring translational cognitive science for stroke recoveryK24HD062647 · NICHD · KESSLER FOUNDATION, INC. · PI BARRETT, A. M. · 2010 to 2014
$695k
NICHD NIH HHS K24 HD062647NINDS NIH HHS R01 NS055808
6 · The paper itself

Abstract

Spatial neglect is a devastating disorder in 50-70% of right-brain stroke survivors, who have problems attending to, or making movements towards, left-sided stimuli, and experience a high risk of chronic dependence. Prism adaptation is a promising treatment for neglect that involves brief, daily visuo-motor training sessions while wearing optical prisms. Its benefits extend to functional behaviors such as dressing, with effects lasting 6 months or longer. Because one to two sessions of prism adaptation induce adaptive changes in both spatial-motor behavior (Fortis et al., 2011) and brain function (Saj et al., 2013), it is possible stroke patients may benefit from treatment periods shorter than the standard, intensive protocol of ten sessions over two weeks-a protocol that is impractical for either US inpatient or outpatient rehabilitation. Demonstrating the effectiveness of a lower dose will maximize the availability of neglect treatment. We present preliminary data suggesting that four to six sessions of prism treatment may induce a large treatment effect, maintained three to four weeks post-treatment. We call for a systematic, randomized clinical trial to establish the minimal effective dose suitable for stroke intervention.

Indexed as

dose-findinginpatient rehabilitationprism adaptationspatial neglect

Identifiers

PMID25983688
PMCPMC4415396
OpenAlexW1973130826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.