Evidence map›Paper›PMID 25983562›Full record

ReviewClinical Medicine Insights. Cardiology2015

Testosterone replacement and cardiovascular safety: no straight and narrow!

Sartaj S Hans, Sandeep S Dhindsa, Rama Chemitiganti

Abstract readReview
In one paragraph

Review in Clinical Medicine Insights. Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sartaj S HansDivision of Cardiology, Department of Internal Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Sandeep S DhindsaDivision of Endocrinology and Metabolism, Department of Internal Medicine, Texas Tech University Health Sciences Center - Permian Basin Campus, Odessa, TX, USA.
Rama ChemitigantiDivision of Endocrinology and Metabolism, Department of Internal Medicine, Texas Tech University Health Sciences Center - Permian Basin Campus, Odessa, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The past decade has seen a tremendous increase in the number of men treated for hypogonadism with the expectation of symptomatic benefit. However, the long-term cardiovascular safety of testosterone replacement remains unknown because retrospective studies of testosterone replacement have been inconsistent, and definitive, prospective, randomized studies are lacking. The purpose of this review is to critically appraise the studies on testosterone replacement and cardiovascular outcomes.

Indexed as

cardiovascular diseasehypogonadismtestosterone

Identifiers

PMID25983562
PMCPMC4412415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.