ArticleScientific reports2015
Brain structural alterations associated with young women with subthreshold depression.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Exploration of brain imaging biomarkers in subthreshold depression patients across different ages: an ALE meta-analysis based on MRI studies.BMC psychiatry · 2025Pooled it
- Structural and functional brain alterations in subthreshold depression: A multimodal coordinate-based meta-analysis.Human brain mapping · 2024Pooled it
- Effects of light therapy on amygdala connectivity and serotoninergic system in young adults with subthreshold depression.Dialogues in clinical neuroscience · 2025Trial
- Dynamic Changes in ALFF and DC in Subthreshold Depression Before and After ICBT Intervention.Neuropsychiatric disease and treatment · 2025Trial
- Radon-related increases in depressive symptoms are explained by amygdala morphology and external locus of control.Neurotoxicology · 2026Article
- The role of the subcortical structures in subthreshold depression: evidence from static and dynamic functional connectivity.Brain structure & function · 2026Article
- Effect of ketamine intervention on hemodynamic responses in patients with treatment-resistant depression.Scientific reports · 2026Article
- The role of altered decision dynamics and dorsolateral prefrontal cortex to amygdala causal circuitry in the aberrant efficacy of emotion suppression in subthreshold depression.Psychological medicine · 2026Article
- Altered static and dynamic functional network connectivity in individuals with subthreshold depression: a large-scale resting-state fMRI study.European archives of psychiatry and clinical neuroscience · 2025Article
- 7 Tesla MRI Reveals Brain Structural Abnormalities and Neural Plasticity in RPGR-Related Retinitis Pigmentosa.Journal of clinical medicine · 2025Article
- Exploring habenular structural connectivity in Parkinson's disease: insights from 7 T MRI study.Journal of neurology · 2024Article
- The prevalence and clinical correlation factors of cognitive impairment in patients with major depressive disorder hospitalized during the acute phase.Frontiers in psychiatry · 2024Article
- Heterogeneity of depression across the socioeconomic spectrum.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Increased thalamic gray matter volume induced by repetitive transcranial magnetic stimulation treatment in patients with major depressive disorder.Frontiers in psychiatry · 2023Article
- Altered spontaneous neural activity in the precuneus, middle and superior frontal gyri, and hippocampus in college students with subclinical depression.BMC psychiatry · 2021Article
- Associations between brain volumetry and relaxometry signatures and the Edmonton Frail Scale in frailty.Quantitative imaging in medicine and surgery · 2021Article
- Structural abnormalities of cingulate cortex in patients with first-episode drug-naïve schizophrenia comorbid with depressive symptoms.Human brain mapping · 2021Article
- Article
- Depressogenic self-schemas are associated with smaller regional grey matter volume in never-depressed preadolescents.NeuroImage. Clinical · 2020Article
- Integrating Clinical and Genomic Analyses of Hippocampal-Prefrontal Circuit Disorder in Depression.Frontiers in genetics · 2020Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuroanatomical abnormalities in patients with major depression disorder (MDD) have been attracted great research attention. However, the structural alterations associated with subthreshold depression (StD) remain unclear and, therefore, require further investigation. In this study, 42 young women with StD, and 30 matched non-depressed controls (NCs) were identified based on two-time Beck Depression Inventory scores. Whole-brain voxel-based morphometry (VBM) and region of interest method were used to investigate altered gray matter volume (GMV) and white matter volume (WMV) among a non-clinical sample of young women with StD. VBM results indicated that young women with StD showed significantly decreased GMV in the right inferior parietal lobule than NCs; increased GMV in the amygdala, posterior cingulate cortex, and precuneus; and increased WMV in the posterior cingulate cortex and precuneus. Together, structural alterations in specific brain regions, which are known to be involved in the fronto-limbic circuits implicated in depression may precede the occurrence of depressive episodes and influence the development of MDD.
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