Evidence map›Paper›PMID 25982598›Full record

ReviewBrain research2015

The evolving roles of pericyte in early brain injury after subarachnoid hemorrhage.

Yujie Chen, Qiang Li, Jiping Tang, Hua Feng, John H Zhang

Abstract readReview
In one paragraph

Review in Brain research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Observational
  5. Review
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  8. Review
  9. A switch in the pathway of TRPC3-mediated calcium influx into brain pericytes contributes to capillary spasms after subarachnoid hemorrhage.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Article
  10. Article
  11. Pathophysiology, Management, and Therapeutics in Subarachnoid Hemorrhage and Delayed Cerebral Ischemia: An Overview.Pathophysiology : the official journal of the International Society for Pathophysiology · 2023
    Review
  12. Review
  13. Review
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  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yujie ChenDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, China.
Qiang LiDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, China.
Jiping TangDepartment of Physiology and Pharmacology, Loma Linda University, Loma Linda, CA, USA.
Hua FengDepartment of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, China.
John H ZhangDepartment of Physiology and Pharmacology, Loma Linda University, Loma Linda, CA, USA. Electronic address: johnzhang3910@yahoo.com.

Funding

Vascular Biology Core FacilityP01NS082184 · NINDS · LOMA LINDA UNIVERSITY · PI PEARCE, WILLIAM J. · 2014 to 2018
$6.1M
Crotalus Snake Venom Preconditioning to Prevent Surgical Brain InjuryR01NS084921 · NINDS · LOMA LINDA UNIVERSITY · PI ZHANG, JOHN H · 2014 to 2018
$1.7M
Neurovascular Protection for Early Brain Injury after SAHR01NS081740 · NINDS · LOMA LINDA UNIVERSITY · PI ZHANG, JOHN H · 2013 to 2017
$1.6M
NINDS NIH HHS NS081740NINDS NIH HHS NS084921NINDS NIH HHS P01 NS082184NINDS NIH HHS R01 NS081740NINDS NIH HHS R01 NS084921
6 · The paper itself

Abstract

Despite accumulated understanding on the mechanisms of early brain injury and improved management of subarachnoid hemorrhage (SAH), it is still one of the serious and refractory health problems around the world. Traditionally, pericyte, served as capillary contraction handler, is recently considered as the main participant of microcirculation regulation in SAH pathophysiology. However, accumulate evidences indicate that pericyte is much more than we already know. Therefore, we briefly review the characteristics, regulation pathways and functions of pericyte, aim to summarize the evolving new pathophysiological roles of pericyte that are implicated in early brain injury after SAH and to improve our understanding in order to explore potential novel therapeutic options for patients with SAH. This article is part of a Special Issue entitled SI: Cell Interactions In Stroke.

Indexed as

AnimalsBrainHumansPericytesSubarachnoid HemorrhageEarly brain injuryPericyteSubarachnoid hemorrhageVascular neural network

Identifiers

PMID25982598
PMCPMC4569518

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.