SynthesisHeart failure reviews2015
Frailty in advanced heart failure: a systematic review.
Synthesis in Heart failure reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 4 syntheses or guidelines pooled it, 114 citations in OpenAlex.
- Primary care interventions to address physical frailty among community-dwelling adults aged 60 years or older: A meta-analysis.PloS one · 2020Pooled it
- Impact of Frailty on Mortality and Hospitalization in Chronic Heart Failure: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2018Pooled it
- The Relationship between Anaemia and Frailty: A Systematic Review and Meta-Analysis of Observational Studies.The journal of nutrition, health & aging · 2018Pooled it
- The prevalence of frailty in heart failure: A systematic review and meta-analysis.International journal of cardiology · 2017Pooled it
- Integrating a Palliative Approach into Cardiogeriatric Decision-Making for Frail Older Adults with Heart Failure.Geriatrics (Basel, Switzerland) · 2026Review
- Core Competencies of the Modern Geriatric Cardiologist: A Framework for Comprehensive Cardiovascular Care in Older Adults.Journal of clinical medicine · 2026Review
- Clinical Pharmacology of Heart Failure in Frailty.European cardiology · 2026Review
- Cardiovascular Prehabilitation in Patients Awaiting Heart Transplantation- Addressing Clinical Needs (the PREHAB HTx Study).CJC open · 2025Article
- Novel predictors of infection-related rehospitalization in older patients with heart failure in Japan.Geriatrics & gerontology international · 2025Article
- Frailty and Heart Failure: Clinical Insights, Patient Outcomes and Future Directions.Cardiac failure review · 2025Review
- The five times sit-to-stand test predicts achievable exercise intensity during stress echocardiography.European heart journal. Imaging methods and practice · 2025Article
- The Relationship Between Rehabilitation and Frailty in Advanced Heart or Lung Disease.Transplantation direct · 2024Article
- Left Ventricular Diastolic Dysfunction Is Associated with Poor Functional Outcomes after Endovascular Thrombectomy.Journal of cardiovascular development and disease · 2024Article
- Impact of Fried Frailty Phenotype on Postoperative Outcomes After Durable Contemporary Mechanical Circulatory Support: A Single-Center Experience.Cardiology research · 2022Article
- Frailty and solid-organ transplant candidates: a scoping review.BMC geriatrics · 2022Article
- Composite Biomarkers for Assessing Frailty Status in Stable Older Adults With Cardiovascular Disease.Circulation reports · 2022Article
- Physical, Psychological and Social Frailty Are Predictive of Heart Failure: A Cross-Sectional Study.Journal of clinical medicine · 2022Article
- Proteinuria as a Nascent Predictor of Frailty Among People With Metabolic Syndrome: A Retrospective Observational Study.Frontiers in public health · 2022Observational
- Association of frailty with in-hospital outcomes in elderly patients with heart failure.World journal of clinical cases · 2021Article
- Association of adipokines with frailty in heart failure.Acta bio-medica : Atenei Parmensis · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty is a common geriatric syndrome of increased vulnerability to adverse events. The prevalence of frailty among chronic heart failure (CHF) is high and confers a greater risk of adverse events including falls, hospitalisation and mortality. There have been few studies assessing frailty in CHF. A review of the key databases was conducted from 2004 to 2014 including the key search terms 'frail elderly' and 'heart failure'. The following electronic databases were searched: Medline, Cumulative Index for Nursing and Allied Health and Academic Search Complete, with reference lists being manually searched. Articles were included if frailty was assessed using a valid measuring tool in a population with a confirmed diagnosis of CHF. The search yielded a total of 393 articles with 8 articles being selected for review. The prevalence of frailty among those with CHF was high, ranging from 18 to 54 %. The frailty phenotype and geriatric assessments tools were the most common frailty measures utilised; high rates of co-morbidity, hospitalisation and mortality were identified. Frailty is common in CHF and is associated with adverse outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.