Evidence map›Paper›PMID 25980599›Full record

ArticleJournal of substance abuse treatment2015

Prior Experience with Non-Prescribed Buprenorphine: Role in Treatment Entry and Retention.

Laura B Monico, Shannon Gwin Mitchell, Jan Gryczynski, Robert P Schwartz, Kevin E O'Grady, Yngvild K Olsen, Jerome H Jaffe

Open access · bronzeAbstract read
In one paragraph

Article in Journal of substance abuse treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Laura B MonicoFriends Research Institute, 1040 Park Ave., Suite 103, Baltimore, MD, 21201, USA. Electronic address: lmonico@friendsresearch.org.
Shannon Gwin MitchellFriends Research Institute, 1040 Park Ave., Suite 103, Baltimore, MD, 21201, USA. Electronic address: smitchell@friendsresearch.org.
Jan GryczynskiFriends Research Institute, 1040 Park Ave., Suite 103, Baltimore, MD, 21201, USA. Electronic address: jgryczynski@friendsresearch.org.
Robert P SchwartzFriends Research Institute, 1040 Park Ave., Suite 103, Baltimore, MD, 21201, USA. Electronic address: rschwartz@friendsresearch.org.
Kevin E O'GradyDepartment of Psychology, University of Maryland, Biology/Psychology Building, College Park, MD, 20742, USA. Electronic address: keogradyfri@gmail.com.
Yngvild K OlsenInstitute for Behavior Resources REACH Health Services, 2104 Maryland Ave., Baltimore, MD, 21218, USA. Electronic address: yolsen@gmail.com.
Jerome H JaffeFriends Research Institute, 1040 Park Ave., Suite 103, Baltimore, MD, 21201, USA; University of Maryland School of Medicine, Department of Psychiatry, 110 South Paca St. 4th floor, Baltimore, MD, USA. Electronic address: jhjaffe@aol.com.
Friends Research Institute · USInstitutes for Behavior Resources · USUniversity of Maryland, Baltimore · USUniversity of Maryland, College Park · US

Funding

Intensive Outpatient v. Outpatient Treatment with Buprenorphine among African AmeRC1DA028407 · NIDA · FRIENDS RESEARCH INSTITUTE, INC. · PI MITCHELL, SHANNON GWIN · 2009 to 2010
$990k
NIDA NIH HHS 5RC1DA028407NIDA NIH HHS RC1 DA028407
6 · The paper itself

Abstract

Buprenorphine availability continues to expand as an effective treatment for opioid dependence, but increases in availability have also been accompanied by increases in non-prescribed use of the medication. Utilizing data from a randomized clinical trial, this mixed-method study examines associations between use of non-prescribed buprenorphine and subsequent treatment entry and retention. Quantitative analyses (N = 300 African American buprenorphine patients) found that patients with prior use of non-prescribed buprenorphine had significantly higher odds of remaining in treatment through 6 months than patients who were naïve to the medication upon treatment entry. Qualitative data, collected from a subsample of participants (n = 20), identified three thematic explanations for this phenomenon: 1) perceived effectiveness of the medication; 2) cost of obtaining prescription buprenorphine compared to purchasing non-prescribed medication; and 3) convenience of obtaining the medication via daily-dosing or by prescription compared to non-prescribed buprenorphine. These findings suggest a dynamic relationship between non-prescribed buprenorphine use and treatment that indicates potential directions for future research into positive and negative consequences of buprenorphine diversion.

Indexed as

Drug PrescriptionsMedication AdherenceAdultBlack or African AmericanBuprenorphineFemaleHumansMaleMiddle AgedNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersRandomized Controlled Trials as TopicBuprenorphineNarcotic AntagonistsBuprenorphineBuprenorphine diversionOpioid dependenceTreatment retention

Identifiers

PMID25980599
PMCPMC4561018
OpenAlexW2113752259

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.