Evidence map›Paper›PMID 25980409›Full record

SynthesisLipids in health and disease2015

Increased serum resistin levels correlate with psoriasis: a meta-analysis.

Huiyun Huang, Erdong Shen, Shiqing Tang, Xingyou Tan, Xiuli Guo, Qiang Wang, Hongwei Ding

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Lipids in health and disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Ozonated autohemotherapy elevates PPAR-γ expression in CD4American journal of translational research · 2021
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Huiyun HuangDermatological Department, the First People's Hospital of YueYang, Dong Mao Ling Road No.39, YueYang, 414000, P.R. China. huanghuiyun0416@163.com.
Erdong ShenDepartment of Oncology, the First People's Hospital of YueYang, YueYang, 414000, P.R. China. shenerdong0416@163.com.
Shiqing TangDermatological Department, the First People's Hospital of YueYang, Dong Mao Ling Road No.39, YueYang, 414000, P.R. China. tangshiqing0416@163.com.
Xingyou TanDermatological Department, the First People's Hospital of YueYang, Dong Mao Ling Road No.39, YueYang, 414000, P.R. China. tanxingyou504@163.com.
Xiuli GuoDermatological Department, the First People's Hospital of YueYang, Dong Mao Ling Road No.39, YueYang, 414000, P.R. China. guoxiuli619@163.com.
Qiang WangDermatological Department, the First People's Hospital of YueYang, Dong Mao Ling Road No.39, YueYang, 414000, P.R. China. wangqiangwq619@163.com.
Hongwei DingDermatological Department, the First People's Hospital of YueYang, Dong Mao Ling Road No.39, YueYang, 414000, P.R. China. dinghongwei619@163.com.
Yueyang Second People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies implicate adipokines in the pathogenesis of inflammatory diseases, including psoriasis. In this study we evaluated the significance of serum resistin levels in psoriasis patients using a meta-analysis approach.223

methodsRelevant articles were retrieved by searching the following English and Chinese databases: Cochrane Library, PubMed, Springer Link, Chinese Biomedical Database (CBM) and Chinese National Knowledge Infrastructure (CNKI). The retrieved studies were subjected to a thorough screening procedure to identify case-control studies that contained the required data. Data was extracted from each study and Version 12.0 STATA statistical software was employed for statistical analyses.

resultsNine case-control studies, containing 421 psoriasis patients and 348 healthy controls, were included in this study. The major result of the meta-analysis revealed a statistically significant association between serum resistin levels and psoriasis (SMD=2.22, 95%CI: 1.14-3.29, P<0.001). Subgroup analysis based on ethnicity showed that, compared to the healthy controls, serum resistin levels were markedly higher in psoriasis patients in both Asian and Caucasian populations (Asians: SMD=3.27, 95%CI=1.62~4.91, P<0.001; Caucasians: SMD=0.91, 95%CI=0.28~1.54, P<0.001).

conclusionsBased on our results, we conclude that serum resistin level in psoriasis patients is higher than healthy controls, and raises the possibility that elevated serum resistin levels may be a novel diagnostic marker in psoriasis and may predict the occurrence of co-morbidities in psoriasis patients.

Indexed as

AdultFemaleHumansMaleMiddle AgedPsoriasisResistinResistin

Identifiers

PMID25980409
PMCPMC4451955
OpenAlexW2118427661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.