Evidence map›Paper›PMID 25979820›Full record

ReviewClinical immunology (Orlando, Fla.)2015

Proteomics and autoimmune kidney disease.

Brad H Rovin, Jon B Klein

Abstract readReview
In one paragraph

Review in Clinical immunology (Orlando, Fla.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A systems approach to renal inflammation in SLE.Clinical immunology (Orlando, Fla.) · 2017
    Review
  6. What is damaging the kidney in lupus nephritis?Nature reviews. Rheumatology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Brad H RovinNephrology Division, The Ohio State University Wexner Medical Center, Columbus, OH, United States. Electronic address: Rovin.1@osu.edu.
Jon B KleinNephrology Division, The University of Louisville School of Medicine, Robley Rex VA Medical Center, Louisville, KY, United States.

Funding

Discovery & Validation of Biomarkers of Kidney PathologyU01DK096927 · NIDDK · OHIO STATE UNIVERSITY · PI ROVIN, BRAD H · 2013 to 2017
$2.0M
NIDDK NIH HHS U01 DK096927
6 · The paper itself

Abstract

Proteomics has long been considered an ideal platform, and urine an ideal source for biomarker discovery in human autoimmune kidney diseases. A number of studies have examined the urine proteome to identify biomarkers of disease activity, kidney pathology, and response to therapy. Increasingly, proteomic studies of kidney disease have expanded to include blood, circulating cells and kidney tissue. Recently the clinical potential of renal proteomics has been realized through a handful of investigations whose results appear to be applicable to patient care. In this review, approaches to the proteomic evaluation of autoimmune kidney diseases will be considered in the context of developing clinically useful disease biomarkers.

Indexed as

ProteomicsAutoimmune DiseasesBiomarkersChromatography, LiquidElectrophoresis, Gel, Two-DimensionalHumansKidney DiseasesProteomeSensitivity and SpecificityTandem Mass SpectrometryBiomarkersProteomeProteomics

Identifiers

PMID25979820
PMCPMC4628556

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.