ReviewSeminars in perinatology2015
Detection of critical congenital heart defects: Review of contributions from prenatal and newborn screening.
Review in Seminars in perinatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Associations between IL-1α, IL-1β, TNFα, and IL-6 variations, and susceptibility to transposition of the great arteries.BMC cardiovascular disorders · 2022Trial
- National Trends and Disparities in Congenital Heart Disease Mortality in the United States, 1999-2024.Pediatric cardiology · 2026Article
- Outcomes of Congenital Heart Disease Deliveries at a Freestanding Children's Hospital.Pediatric cardiology · 2026Article
- Newborn Critical Congenital Heart Disease Screening Using Pulse Oximetry in a Global Context: Progress, Disparities, and the Importance of Early Detection.International journal of neonatal screening · 2026Article
- The Heart's Small Molecules: The Importance of MicroRNAs in Cardiovascular Health.Journal of clinical medicine · 2025Review
- Prospective Evaluation of Pulse Oximetry Screening for Critical Congenital Heart Disease in a Jordanian Tertiary Hospital: High Incidence and Early Detection Challenges.Pediatric reports · 2025Article
- Evaluation of Integrated Service Strategy Based on Diagnosis of Duct-Dependent Congenital Heart Disease and Neonatal Mortality Data Analysis - Beijing, China, 2021-2022.China CDC weekly · 2025Article
- Artificial intelligence-driven framework for improving prenatal screening for congenital heart disease in rural Nebraska.Frontiers in pediatrics · 2025Article
- Development and validation of a prenatal predictive nomogram for the risk of NICU admission in infants born to Chinese mothers over 35 years of age: a retrospective cohort study.BMC pregnancy and childbirth · 2024Article
- Neonatal Outcomes of Critical Congenital Heart Defects: A Multicenter Epidemiological Study of Turkish Neonatal Society : Neonatal Outcomes of CCHD.Pediatric cardiology · 2024Article
- Evaluation of critical congenital heart disease from 2018 to 2020 in Turkey: a retrospective cohort study.BMC pregnancy and childbirth · 2023Article
- New Insights into the Education of Children with Congenital Heart Disease with and without Trisomy 21.Medicina (Kaunas, Lithuania) · 2023Article
- An Insight into Indonesia's Challenges in Implementing Newborn Screening Programs and Their Future Implications.Children (Basel, Switzerland) · 2023Review
- Spectrum of congenital heart disease in Nepal from 2002-2022: A systematic review and meta-analysis.Health science reports · 2023Article
- Article
- Impact of an electronic medical record-based automated screening program for critical congenital heart disease: Emirates Health Services, United Arab Emirates.BMC medical informatics and decision making · 2022Observational
- Prenatal Detection of Congenital Heart Diseases Using Echocardiography: 12-Year Results of an Improving Program With 9782 Cases.Frontiers in public health · 2022Article
- 'Superimposed miracles': an extremely rare case of a septuagenarian with an unrepaired tetralogy of Fallot: a case report.European heart journal. Case reports · 2021Article
- Maternal sociodemographic characteristics, early pregnancy behaviours, and livebirth outcomes as congenital heart defects risk factors - Northern Ireland 2010-2014.BMC pregnancy and childbirth · 2021Article
- Delayed diagnosis of critical congenital heart defects predicting risk factors and survival rate in newborns in Beijing: a retrospective study.The Journal of international medical research · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
In 2011, statewide newborn screening programs for critical congenital heart defects began in the United States, and subsequently screening has been implemented widely. In this review, we focus on data reports and collection efforts related to both prenatal diagnosis and newborn screening. Defect-specific, maternal, and geographic factors are associated with variations in prenatal detection, so newborn screening provides a population-wide safety net for early diagnosis. A new web-based repository is collecting information on newborn screening program policies, quality indicators related to screening programs, and specific case-level data on infants with these defects. Birth defects surveillance programs also collect data about critical congenital heart defects, particularly related to diagnostic timing, mortality, and services. Individuals from state programs, federal agencies, and national organizations will be interested in these data to further refine algorithms for screening in normal newborn nurseries, neonatal intensive care settings, and other special populations; and ultimately to evaluate the impact of screening on outcomes.
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