Evidence map›Paper›PMID 25979644›Full record

ArticleDrug and alcohol dependence2015

A reexamination of medical marijuana policies in relation to suicide risk.

Richard A Grucza, Michael Hur, Arpana Agrawal, Melissa J Krauss, Andrew D Plunk, Patricia A Cavazos-Rehg, Frank J Chaloupka, Laura J Bierut

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Largest Epidemiological Study not Mentioned.Deutsches Arzteblatt international · 2016
    Article
  13. Medical Marijuana Laws and Suicide.American journal of public health · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Richard A GruczaDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: gruczar@psychiatry.wustl.edu.
Michael HurDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Arpana AgrawalDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Melissa J KraussDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Andrew D PlunkDepartment of Pediatrics, Eastern Virginia Medical School, Norfolk, VA, USA.
Patricia A Cavazos-RehgDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Frank J ChaloupkaDepartment of Economics and Health Policy Center, University of Illinois at Chicago, Chicago, IL, USA.
Laura J BierutDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO, USA.

Funding

The Collaborative Genetic Study of Nicotine DependenceP01CA089392 · NCI · WASHINGTON UNIVERSITY · PI BIERUT, LAURA J. · 2001 to 2012
$17.3M
Genetics Study of Nicotine Dependence in African AmericansR01DA025888 · NIDA · WASHINGTON UNIVERSITY · PI BIERUT, LAURA J., JOHNSON, ERIC OTTO · 2009 to 2014
$4.7M
Nicotine Dependence to Smoking Cessation: Sequencing Common and Rare VariantsR01DA036583 · NIDA · WASHINGTON UNIVERSITY · PI BIERUT, LAURA J. · 2014 to 2017
$3.0M
BUILDING ON BRIDGING THE GAP: ENVIRONMENTAL INFLUENCES ON TEEN SUBSTANCE USER01DA032843 · NIDA · WASHINGTON UNIVERSITY · PI CAVAZOS-REHG, PATRICIA A · 2012 to 2015
$1.5M
POLICY AS ENVIRONMENT : LONG-TERM EFFECTS OF LAWS RESTRICTING YOUTH SUBSTANCE USER01DA031288 · NIDA · WASHINGTON UNIVERSITY · PI GRUCZA, RICHARD A · 2012 to 2015
$1.1M
NCI NIH HHS P01 CA089392NIDA NIH HHS R01 DA031288NIDA NIH HHS R01 DA032843NIDA NIH HHS R01 DA036583
6 · The paper itself

Abstract

objectivesPrevious research has suggested that medical marijuana policies lead to reductions in suicide rates. In this study, we further investigate the association between these policies and within-state changes in suicide risk.

methodsData on suicide deaths (n=662,993) from the National Vital Statistics System Multiple Cause of Death files were combined with living population data. Fixed-effects regression methods were employed to control for state differences in suicide rates and national and state secular trends. Analyses extended prior research that suggested a protective effect of medical marijuana policies by incorporating newer data and additional covariates.

resultsAfter adjustment for race/ethnicity, tobacco control policies, and other covariates, we found no association between medical marijuana policy and suicide risk in the population ages 15 and older (OR=1.000; 95% CI: 0.956, 1.045; p=0.98), among men overall (OR=0.996; 95% CI: 0.951, 1.043; p=0.87) or for any other age-by-sex groups.

conclusionWe find no statistically significant association between medical marijuana policy and suicide risk. These results contradict prior analyses which did not control for race/ethnicity and certain state characteristics such as tobacco control policies. Failure to control for these factors in future analyses would likely bias estimates of the associations between medical marijuana policy and health outcomes.

Indexed as

Health PolicyAdolescentAdultAgedFemaleHumansMaleMedical MarijuanaMiddle AgedSuicideUnited StatesYoung AdultMedical MarijuanaEpidemiologyMarijuanaMedical marijuanaPolicySuicide

Identifiers

PMID25979644
PMCPMC4459507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.