Evidence map›Paper›PMID 25979318›Full record

Trial reportContemporary clinical trials2015

A randomized controlled exercise training trial on insulin sensitivity in African American men: The ARTIIS study: Major category: study design, statistical design, study protocols.

Robert L Newton, William D Johnson, Chelsea Hendrick, Melissa Harris, Emanuel Andrews, Neil Johannsen, Ruben Q Rodarte, Daniel S Hsia, Timothy S Church

Registry-linked trialOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01787617 (Aerobic Plus Resistance Training and Insulin Sensitivity in African American Men), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01787617 nacompletednot on this map

Aerobic Plus Resistance Training and Insulin Sensitivity in African American Men

TypeinterventionalSponsorPennington Biomedical Research CenterRan2012 to 2018Enrolled113ConditionsInsulin Resistance, Type 2 DiabetesArmsAerobic Plus Resistance Training Group, Control Group
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Robert L NewtonPennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA. Electronic address: Robert.Newton@pbrc.edu.
William D JohnsonPennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA. Electronic address: William.Johnson@pbrc.edu.
Chelsea HendrickPennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA. Electronic address: Chelsea.Hendrick@pbrc.edu.
Melissa HarrisPennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA. Electronic address: Melissa.Harris@pbrc.edu.
Emanuel AndrewsPennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA. Electronic address: Emanuel.Andrews@pbrc.edu.
Neil JohannsenPennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA; Louisiana State University, 112 Huey P. Long Field House, Baton Rouge, LA, 70803, USA. Electronic address: njohan1@lsu.edu.
Ruben Q RodartePennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA; ACAP Health, 12712 Park Central Dr., Suite 100, Dallas, TX 75251, USA. Electronic address: RRodarte@acaphealth.com.
Daniel S HsiaLouisiana State University, 112 Huey P. Long Field House, Baton Rouge, LA, 70803, USA. Electronic address: Daniel.Hsia@pbrc.edu.
Timothy S ChurchPennington Biomedical Research Center, 6400 Perkins Rd., Baton Rouge, LA 70808, USA; ACAP Health, 12712 Park Central Dr., Suite 100, Dallas, TX 75251, USA. Electronic address: Timothy.Church@pbrc.edu.
Pennington Biomedical Research Center · USLouisiana State University · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Aerobic Plus Resistance Training to Increase Insulin Sensitivity in African AmeriR01DK095233 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI NEWTON, ROBERT LEE · 2012 to 2015
$1.5M
NIDDK NIH HHS R01 DK095233NIGMS NIH HHS 1 U54 GM104940NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

backgroundLack of regular physical activity at prescribed intensity levels is a modifiable risk factor for insulin resistance and the development of diabetes. African American men are at increased risk for developing diabetes and most African American men are not meeting the current recommended levels of physical activity. The primary objective of the Aerobic Plus Resistance Training and Insulin Resistance in African American Men (ARTIIS) study is to determine the effectiveness of an exercise training intervention aimed at reducing diabetes risk factors in African American men at risk for developing diabetes.

methodsInsufficiently active 35-70 year old African American men with a family history of diabetes were eligible for the study. The 5-month randomized controlled trial assigns 116 men to an exercise training or healthy living control arm. The exercise training arm combines aerobic and resistance training according to the current national physical activity recommendations and is conducted in community (YMCA) facilities. The healthy living arm receives information promoting healthy lifestyle changes. OUTCOMES: Insulin response to an oral glucose load is the primary outcome measure, and changes in physiological parameters, cardiorespiratory fitness, strength, body composition, and psychological well-being comprise the secondary outcomes.

conclusionsThe ARTIIS study is one of the first adequately powered, rigorously designed studies to investigate the effects of an aerobic plus resistance exercise training program and to assess adherence to exercise training in community facilities, in African American men.

Indexed as

Black or African AmericanExerciseInsulin ResistanceResearch DesignAdultAgedBlood GlucoseBody CompositionBody Mass IndexDiabetes Mellitus, Type 2Genetic Predisposition to DiseaseHumansLife StyleMaleMiddle AgedMuscle StrengthBlood GlucoseAfrican AmericanCommunityDiabetes riskExercise trainingMale

Identifiers

PMID25979318
PMCPMC4522375
OpenAlexW2194607728

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.