Evidence map›Paper›PMID 25979176›Full record

ReviewFEBS letters2015

Neuronal responses to stress and injury in C. elegans.

Kyung Won Kim, Yishi Jin

Abstract readReview
In one paragraph

Review in FEBS letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. eNeuro · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Sleep Analysis in AdultThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  14. Article
  15. Reactive Oxygen Species Modulate Activity-Dependent AMPA Receptor Transport inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  16. Article
  17. Effects of NADBiomolecules · 2020
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kyung Won KimSection of Neurobiology, Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093, United States. Electronic address: k9kim@ucsd.edu.
Yishi JinSection of Neurobiology, Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093, United States; Howard Hughes Medical Institute, University of California San Diego, La Jolla, CA 92093, United States. Electronic address: yijin@ucsd.edu.

Funding

GABAERGIC NEURON DIFFERENTIATION IN C ELEGANSR01NS035546 · NINDS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI JIN, YISHI · 1996 to 2016
$5.3M
Development of a C. elegans model for axonal regenerationR01NS057317 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHISHOLM, ANDREW D · 2009 to 2013
$1.5M
Development of a C.elegans model for axonal regenerationR56NS057317 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHISHOLM, ANDREW D, JIN, YISHI · 2014 to 2014
$388k
Howard Hughes Medical InstituteNINDS NIH HHS R01 NS035546NINDS NIH HHS R01 NS057317NINDS NIH HHS R56 NS057317
6 · The paper itself

Abstract

The nervous system plays critical roles in the stress response. Animals can survive and function under harsh conditions, and resist and recover from injuries because neurons perceive and respond to various stressors through specific regulatory mechanisms. Caenorhabditis elegans has served as an excellent model to discover fundamental mechanisms underlying the neuronal response to stress. The basic physiological processes that C. elegans exhibits under stress conditions are similar to those observed in higher organisms. Many molecular pathways activated by environmental and cellular stresses are also conserved. In this review, we summarize major findings in examining neuronal responses to hypoxia, oxidative stress, osmotic stress, and traumatic injury. These studies from C. elegans have provided novel insights into our understanding of neuronal responses to stress at the molecular, cellular, and circuit levels.

Indexed as

Stress, PhysiologicalAnimalsCaenorhabditis elegansNeuronsOsmotic PressureOxidative StressWounds and InjuriesAxon regenerationHypoxiaNeurodegenerationOsmotic stressOxidative stressStress responseTraumatic injury

Identifiers

PMID25979176
PMCPMC4458507

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.