ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2015
Bispectral Index in Evaluating Effects of Sedation Depth on Drug-Induced Sleep Endoscopy.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Upper Airway Collapsibility Evaluation in Different Sedative Levels by Sleep Endoscopy
Propofolsleep - A Observational Study on Cardiopulmonary and Pharyngeal Reactions While Drug Induced Sleep Endoscopy in Patients With Obstructive Sleep Apnea Syndrome Under PSI Monitoring
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Drug-induced sleep endoscopy in obstructive sleep apnea: a systematic review and meta-analysis of sedative agents, monitoring methods, and administration techniques.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Pooled it
- Hypoventilation patterns during bronchoscopic sedation and their clinical relevance based on capnographic and respiratory impedance analysis.Journal of clinical monitoring and computing · 2020Trial
- Capnography monitoring the hypoventilation during the induction of bronchoscopic sedation: A randomized controlled trial.Scientific reports · 2017Trial
- PFA Under Deep Sedation and Non-Invasive Monitoring in Atrial Fibrillation Patients With Obstructive Sleep Apnea.Pacing and clinical electrophysiology : PACE · 2026Article
- Metabolic Improvements Following Upper Airway Surgery in Obstructive Sleep Apnea: Association of Airway Improvement with Insulin Resistance.Journal of clinical medicine · 2026Article
- Adaptive PK/PD model optimization: a comparative analysis of bounded optimization methods for individual BIS prediction.Journal of pharmacokinetics and pharmacodynamics · 2026Article
- Tongue Pressure as a Predictor of Tongue Base Collapse in Patients with Obstructive Sleep Apnea Syndrome.Biomedicines · 2026Article
- Controversial Aspects in Sedative Techniques for Drug-Induced Sleep Endoscopy (DISE)-A Narrative Review.Medical sciences (Basel, Switzerland) · 2026Review
- Article
- The Repeatability of Pharyngeal Opening Pressure Under Drug-Induced Sleep Endoscopy.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024Article
- Bispectral Index versus the University of Michigan Sedation Scale in assessing sedation depth during pediatric drug-induced sleep endoscopy.Sleep & breathing = Schlaf & Atmung · 2024Article
- The influence of different application patterns of propofol on the sedation courses during drug-induced sleep endoscopy.Laryngoscope investigative otolaryngology · 2024Article
- The effect of head of bed elevation on upper airway collapsibility during drug-induced sleep endoscopy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- The clinical application progress and potential of drug-induced sleep endoscopy in obstructive sleep apnea.Annals of medicine · 2022Review
- Outcome of CPAP Titration for Moderate-to-Severe OSA Under Drug-Induced Sleep Endoscopy: A Randomized Controlled Crossover Trial.Frontiers in neurology · 2022Article
- The safety and efficacy of esketamine in comparison to dexmedetomidine during drug-induced sleep endoscopy in children with obstructive sleep apnea hypopnea syndrome: A randomized, controlled and prospective clinical trial.Frontiers in pharmacology · 2022Article
- Sound frequency spectra of snore in relation to the site of obstruction among snorers.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2021Article
- Depth of sedation during drug induced sedation endoscopy monitored by BiSpectral Index® and Cerebral State Index®.Sleep & breathing = Schlaf & Atmung · 2021Article
- The Use of Middle Latency Auditory Evoked Potentials (MLAEP) as Methodology for Evaluating Sedation Level in Propofol-Drug Induced Sleep Endoscopy (DISE) Procedure.International journal of environmental research and public health · 2021Article
- Comparison of Drug-Induced Sleep Endoscopy and Natural Sleep Endoscopy in the Assessment of Upper Airway Pathophysiology During Sleep: Protocol and Study Design.Frontiers in neurology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effect of sedation depth on drug-induced sleep endoscopy (DISE).
methodsNinety patients with obstructive sleep apnea (OSA) and 18 snorers underwent polysomnography and DISE under bispectral index (BIS)-guided propofol infusion at two different sedation levels: BIS 65-75 (light sedation) and 50-60 (deep sedation).
resultsFor the patients with OSA, the percentages of velopharynx, oropharynx, hypopharynx, and larynx obstructions under light sedation were 77.8%, 63.3%, 30%, and 33.3%, respectively. Sedation depth was associated with the severity of velopharynx and oropharynx obstruction, oropharynx obstruction pattern, tongue base obstruction, epiglottis anteroposterior prolapse and folding, and arytenoid prolapse. In comparison, OSA severity was associated with the severity of velopharynx obstruction, severity of oropharynx obstruction, and arytenoid prolapse (odds ratio (95% confidence interval); 14.3 (4.7-43.4), 11.7 (4.2-32.9), and 13.2 (2.8-62.3), respectively). A good agreement was noted between similar DISE findings at different times and different observers (kappa value 0.6 to 1, respectively). A high percentage of arytenoid prolapse (46.7% among the patients with OSA under light sedation) was noted.
conclusionsGreater sedative depth increased upper airway collapsibility under DISE assessment. DISE under BIS-guided propofol infusion, and especially a level of 65-75, offers an objective and reproducible method to evaluate upper airway collapsibility. Some findings were induced by drug sedation and need careful interpretation. Specific arytenoid prolapse patterns were noted for which further investigations are warranted. CLINICAL TRIALS REGISTRATION: http://www.clinicaltrials.gov, identifier: NCT01100554. COMMENTARY: A commentary on this article appears in this issue on page 965.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.