Evidence map›Paper›PMID 25979068›Full record

ArticleMedical physics2015

Accelerated statistical reconstruction for C-arm cone-beam CT using Nesterov's method.

Adam S Wang, J Webster Stayman, Yoshito Otake, Sebastian Vogt, Gerhard Kleinszig, Jeffrey H Siewerdsen

Open access · bronzeAbstract read
In one paragraph

Article in Medical physics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

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  14. An Investigation of Low-Dose 3D Scout Scans for Computed Tomography.Proceedings of SPIE--the International Society for Optical Engineering · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Adam S WangDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205.
J Webster StaymanDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205.
Yoshito OtakeDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205.
Sebastian VogtSiemens Healthcare XP Division, Erlangen, 91052, Germany.
Gerhard KleinszigSiemens Healthcare XP Division, Erlangen, 91052, Germany.
Jeffrey H SiewerdsenDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205.
Johns Hopkins University · USSiemens Healthcare (Germany) · DE

Funding

Intraoperative Imaging for Guidance, Patient Safety, and OR Quality AssuranceR01EB017226 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI SIEWERDSEN, JEFFREY H · 2014 to 2017
$2.1M
C-Arm CBCT with Model-Based Image Reconstruction for Neurosurgical InterventionsF32EB017571 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI WANG, ADAM S · 2013 to 2013
$41k
NIBIB NIH HHS F32 EB017571NIBIB NIH HHS F32EB017571NIBIB NIH HHS R01 EB017226
6 · The paper itself

Abstract

purposeTo accelerate model-based iterative reconstruction (IR) methods for C-arm cone-beam CT (CBCT), thereby combining the benefits of improved image quality and/or reduced radiation dose with reconstruction times on the order of minutes rather than hours.

methodsThe ordered-subsets, separable quadratic surrogates (OS-SQS) algorithm for solving the penalized-likelihood (PL) objective was modified to include Nesterov's method, which utilizes "momentum" from image updates of previous iterations to better inform the current iteration and provide significantly faster convergence. Reconstruction performance of an anthropomorphic head phantom was assessed on a benchtop CBCT system, followed by CBCT on a mobile C-arm, which provided typical levels of incomplete data, including lateral truncation. Additionally, a cadaveric torso that presented realistic soft-tissue and bony anatomy was imaged on the C-arm, and different projectors were assessed for reconstruction speed.

resultsNesterov's method provided equivalent image quality to OS-SQS while reducing the reconstruction time by an order of magnitude (10.0 ×) by reducing the number of iterations required for convergence. The faster projectors were shown to produce similar levels of convergence as more accurate projectors and reduced the reconstruction time by another 5.3 ×. Despite the slower convergence of IR with truncated C-arm CBCT, comparison of PL reconstruction methods implemented on graphics processing units showed that reconstruction time was reduced from 106 min for the conventional OS-SQS method to as little as 2.0 min with Nesterov's method for a volumetric reconstruction of the head. In body imaging, reconstruction of the larger cadaveric torso was reduced from 159 min down to 3.3 min with Nesterov's method.

conclusionsThe acceleration achieved through Nesterov's method combined with ordered subsets reduced IR times down to a few minutes. This improved compatibility with clinical workflow better enables broader adoption of IR in CBCT-guided procedures, with corresponding benefits in overcoming conventional limits of image quality at lower dose.

Indexed as

AlgorithmsCone-Beam Computed TomographyHeadHumansModels, BiologicalPhantoms, ImagingRadiation DosageRadiography, AbdominalStatistics as TopicSurgery, Computer-AssistedTime Factors

Identifiers

PMID25979068
PMCPMC4425726
OpenAlexW1493336793

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.