ArticleNature chemical biology2015
Application guide for omics approaches to cell signaling.
Article in Nature chemical biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Multiplexed sequential imaging in living cells with orthogonal fluorogenic RNA aptamer/dye pairs.Nucleic acids research · 2024Article
- Magnetogenetics as a promising tool for controlling cellular signaling pathways.Journal of nanobiotechnology · 2024Review
- Fluorescent biosensors illuminate the spatial regulation of cell signaling across scales.The Biochemical journal · 2023Review
- B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer.iScience · 2022Article
- Renal microvascular endothelial cell responses in sepsis-induced acute kidney injury.Nature reviews. Nephrology · 2022Review
- A homogeneous split-luciferase assay for rapid and sensitive detection of anti-SARS CoV-2 antibodies.Nature communications · 2021Article
- Ciguatera Mini Review: 21st Century Environmental Challenges and the Interdisciplinary Research Efforts Rising to Meet Them.International journal of environmental research and public health · 2021Review
- KRSA: An R package and R Shiny web application for an end-to-end upstream kinase analysis of kinome array data.PloS one · 2021Article
- Integrative Network Analysis Revealed Genetic Impact of Pyruvate Kinase L/R on Hepatocyte Proliferation and Graft Survival after Liver Transplantation.Oxidative medicine and cellular longevity · 2021Article
- Split Intein-Mediated Protein Ligation for detecting protein-protein interactions and their inhibition.Nature communications · 2020Article
- Editorial: Multi-Omics Approaches to Study Signaling Pathways.Frontiers in bioengineering and biotechnology · 2020Article
- Kinase network dysregulation in a human induced pluripotent stem cell model of DISC1 schizophrenia.Molecular omics · 2019Article
- Towards a data-integrated cell.Nature communications · 2019Article
- FRETting about the affinity of bimolecular protein-protein interactions.Protein science : a publication of the Protein Society · 2018Article
- Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Review
- GFP-Grb2 Translocation Assay Using High-content Imaging to Screen for Modulators of EGFR-signaling.Bio-protocol · 2017Article
- RNA Polymerase Tags To Monitor Multidimensional Protein-Protein Interactions Reveal Pharmacological Engagement of Bcl-2 Proteins.Journal of the American Chemical Society · 2017Article
- The Root Growth-Regulating Brevicompanine Natural Products Modulate the Plant Circadian Clock.ACS chemical biology · 2017Article
- Proteomic Analysis of Postsynaptic Protein Complexes Underlying Neuronal Plasticity.ACS chemical neuroscience · 2017Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Research in signal transduction aims to identify the functions of different signaling pathways in physiological and pathological states. Traditional techniques using biochemical, genetic or cell biological approaches have made important contributions to our understanding of cellular signaling. However, the single-gene approach does not take into account the full complexity of cell signaling. With the availability of omics techniques, great progress has been made in understanding signaling networks. Omics approaches can be classified into two categories: 'molecular profiling', including genomic, proteomic, post-translational modification and interactome profiling; and 'molecular perturbation', including genetic and functional perturbations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.