ArticlePediatric research2015
Neonatal DTI early after birth predicts motor outcome in preterm infants with periventricular hemorrhagic infarction.
Article in Pediatric research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Epidemiology and pathogenesis of stroke in preterm infants: A systematic review.Journal of neonatal-perinatal medicine · 2022Pooled it
- Feasibility trial of an early therapy in perinatal stroke (eTIPS).BMC neurology · 2018Trial
- Association of germinal matrix hemorrhage volume with neurodevelopment and hydrocephalus.Journal of neurosurgery. Pediatrics · 2024Article
- A regional brain volume-based age prediction model for neonates and the derived brain maturation index.European radiology · 2024Article
- Determinants of cerebral palsy in children: systematic review.Sudanese journal of paediatrics · 2023Review
- Early motor outcomes in infants with critical congenital heart disease are related to neonatal brain development and brain injury.Developmental medicine and child neurology · 2022Article
- Brain MRI radiomics analysis may predict poor psychomotor outcome in preterm neonates.European radiology · 2021Article
- Fronto-temporal horn ratio: yet another marker of ventriculomegaly?Pediatric research · 2021Article
- White matter injury in infants with intraventricular haemorrhage: mechanisms and therapies.Nature reviews. Neurology · 2021Review
- Early prediction of unilateral cerebral palsy in infants at risk: MRI versus the hand assessment for infants.Pediatric research · 2020Article
- Cranial ultrasound findings in preterm germinal matrix haemorrhage, sequelae and outcome.Pediatric research · 2020Review
- Altered neonatal white and gray matter microstructure is associated with neurodevelopmental impairments in very preterm infants with high-grade brain injury.Pediatric research · 2019Article
- In vivo high-resolution diffusion tensor imaging of the developing neonatal rat cortex and its relationship to glial and dendritic maturation.Brain structure & function · 2019Article
- Baby brain atlases.NeuroImage · 2019Review
- Weak functional connectivity in the human fetal brain prior to preterm birth.Scientific reports · 2017Article
- Fifty years of brain imaging in neonatal encephalopathy following perinatal asphyxia.Pediatric research · 2017Review
- Neonatal diffusion tensor brain imaging predicts later motor outcome in preterm neonates with white matter abnormalities.Italian journal of pediatrics · 2016Article
- Diffusion tensor imaging-based assessment of white matter tracts and visual-motor outcomes in very preterm neonates.Neuroradiology · 2016Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo determine the association between early neonatal diffusion tensor imaging (DTI) and the development of unilateral spastic cerebral palsy (USCP) in preterm infants with periventricular hemorrhagic infarction (PVHI).
methodsPreterm infants with PVHI were assessed with early (≤4 wk after birth) and term-equivalent age MRI-DTI. Involvement of corticospinal tracts was assessed by visual assessment of the posterior limb of the internal capsule (PLIC) on DTI (classified asymmetrical, equivocal, or symmetrical) and by an atlas-based approach calculating fractional anisotropy asymmetry index in the PLIC. Motor outcome was assessed at ≥15 mo corrected age.
resultsSeven out of 23 infants with PVHI developed USCP. Their PLIC was visually scored as asymmetrical in 6 and equivocal in 1 on the early DTI. Thirteen out of 16 infants with a symmetrical motor development had a symmetrical PLIC on early DTI, the remaining 3 were equivocal. All infants with USCP had a fractional anisotropy asymmetry index of >0.05 (optimal cut-off value) on early DTI. In infants with a symmetrical motor development (n = 16), 14 had an asymmetry index ≤0.05 while 2 had an index >0.05.
conclusionDTI in preterm infants with PVHI within a few weeks after birth is associated with later motor development.
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