Evidence map›Paper›PMID 25978795›Full record

SynthesisEpidemiology (Cambridge, Mass.)2015

Cannabis Smoking and Diabetes Mellitus: Results from Meta-analysis with Eight Independent Replication Samples.

Omayma Alshaarawy, James C Anthony

Abstract readMeta-Analysis
In one paragraph

Synthesis in Epidemiology (Cambridge, Mass.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. A Review of the Effects of Adolescent Cannabis Use on Physical Health.The Psychiatric clinics of North America · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. A Review of the Effects of Adolescent Cannabis Use on Physical Health.Child and adolescent psychiatric clinics of North America · 2023
    Review
  9. Review
  10. The effects of cannabis and cannabinoids on the endocrine system.Reviews in endocrine & metabolic disorders · 2022
    Review
  11. Cannabis and cannabinoid research · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Omayma AlshaarawyFrom the Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI.
James C Anthony

Funding

Training Program in Drug Dependence EpidemiologyT32DA021129 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2006 to 2016
$2.7M
Drug Dependence Epidemiology and EnviromicsK05DA015799 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2015
$1.4M
NIDA NIH HHS K05 DA015799NIDA NIH HHS K05DA015799NIDA NIH HHS T32 DA021129NIDA NIH HHS T32DA021129
6 · The paper itself

Abstract

backgroundIn preclinical animal studies, evidence links cannabis with hyperphagia, obesity, and insulin resistance. Epidemiologic data, however, suggest an inverse cannabis smoking-diabetes mellitus association. Here, we offer epidemiologic estimates from eight independent replications from (1) the National Health and Nutrition Examination Surveys, and (2) the National Surveys on Drug Use and Health (2005-2012).

methodsFor each national survey participant, computer-assisted self-interviews assess cannabis smoking and physician-diagnosed diabetes mellitus; the National Health and Nutrition Examination Surveys provide additional biomarker values and a composite diabetes diagnosis. Regression analyses produce estimates of cannabis smoking-diabetes associations. Meta-analyses summarize the replication estimates.

resultsRecently active cannabis smoking and diabetes mellitus are inversely associated. The meta-analytic summary odds ratio is 0.7 (95% confidence interval = 0.6, 0.8).

conclusionsCurrent evidence is too weak for causal inference, but there now is a more stable evidence base for new lines of clinical translational research on a possibly protective (or spurious) cannabis smoking-diabetes mellitus association suggested in prior research.

Indexed as

AdultDiabetes MellitusFemaleHumansLogistic ModelsMaleMarijuana SmokingMiddle AgedNutrition SurveysOdds RatioUnited StatesYoung Adult

Identifiers

PMID25978795
PMCPMC4801109

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.