ArticlePloS one2015
Medicinal plants recommended by the world health organization: DNA barcode identification associated with chemical analyses guarantees their quality.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
62 citing papers in PubMed.
- Chemical profiling and evaluation of in vitro antibacterial and antibiotic synergistic activities of Cleistanthus bracteosus Jabl. from Malaysian rainforests.BMC complementary medicine and therapies · 2026Article
- Spleen protective role, Antiplasmodial and Antioxidant activity of Polyalthia longifolia in mice infected with Plasmodium berghei parasite.Veterinary and animal science · 2026Article
- CDMMM: a comprehensive platform of traditional Indian medicinal plant DNA barcodes and metabolite fingerprints database.Scientific reports · 2026Article
- Neuroprotective Potential ofNutrients · 2025Article
- Integrating DNA Barcoding Within an Orthogonal Approach for Herbal Product Authentication: A Narrative Review.Phytochemical analysis : PCA · 2025Review
- A Comprehensive Overview of the Current Status and Advancements in Various Treatment Strategies against Epilepsy.ACS pharmacology & translational science · 2024Review
- Flavonoids and Other Polyphenols: Bioactive Molecules from Traditional Medicine Recipes/Medicinal Plants and Their Potential for Phytopharmaceutical and Medical Application.Molecules (Basel, Switzerland) · 2024Review
- Virulent-MDR-ESBL E. coli and Klebsiella pneumoniae report from North Sinai calves diarrhea and in vitro antimicrobial by Moringa oleifera.BMC veterinary research · 2024Article
- Phytotherapeutic options for the treatment of epilepsy: pharmacology, targets, and mechanism of action.Frontiers in pharmacology · 2024Review
- Prevalence of fatigue and consumption of energy drinks consumption among nursing students studying part-time.Health SA = SA Gesondheid · 2024Article
- Plant-derived nanovesicles: harnessing nature's power for tissue protection and repair.Journal of nanobiotechnology · 2023Review
- Plants of the Rubiaceae Family with Effect on Metabolic Syndrome: Constituents, Pharmacology, and Molecular Targets.Plants (Basel, Switzerland) · 2023Review
- A Scoping Review on Medicinal Properties ofThe Malaysian journal of medical sciences : MJMS · 2023Article
- Nature-Inspired Compounds: Synthesis and Antibacterial Susceptibility Testing of Eugenol Derivatives againstPharmaceuticals (Basel, Switzerland) · 2023Article
- An In Vitro and In Silico Characterization ofPharmaceutics · 2023Article
- Herbal species authentication by melting fingerprint coupled with high resolution melting analysis (MF-HRM).Molecular biology reports · 2023Article
- Article
- Camel Grass Phenolic Compounds: Targeting Inflammation and Neurologically Related Conditions.Molecules (Basel, Switzerland) · 2022Article
- Exploration of facilitators and barriers to the regulatory frameworks of dietary and herbal supplements: a scoping review.Journal of pharmaceutical policy and practice · 2022Article
- Enhancing Testing Laboratory Engagement in Plant DNA Barcoding through a Routine Workflow-A Case Study on Chinese Materia Medica (CMM).Plants (Basel, Switzerland) · 2022Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Medicinal plants are used throughout the world, and the regulations defining their proper use, such as identification of the correct species and verification of the presence, purity and concentration of the required chemical compounds, are widely recognized. Herbal medicines are made from vegetal drugs, the processed products of medicinal species. These processed materials present a number of challenges in terms of botanical identification, and according to the World Health Organization (WHO), the use of incorrect species is a threat to consumer safety. The samples used in this study consisted of the dried leaves, flowers and roots of 257 samples from 8 distinct species approved by the WHO for the production of medicinal herbs and sold in Brazilian markets. Identification of the samples in this study using DNA barcoding (matK, rbcL and ITS2 regions) revealed that the level of substitutions may be as high as 71%. Using qualitative and quantitative chemical analyses, this study identified situations in which the correct species was being sold, but the chemical compounds were not present. Even more troubling, some samples identified as substitutions using DNA barcoding contained the chemical compounds from the correct species at the minimum required concentration. This last situation may lead to the use of unknown species or species whose safety for human consumption remains unknown. This study concludes that DNA barcoding should be used in a complementary manner for species identification with chemical analyses to detect and quantify the required chemical compounds, thus improving the quality of this class of medicines.
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