Evidence map›Paper›PMID 25977840›Full record

ArticleJournal of Alzheimer's disease & Parkinsonism2015

Microbial Sources of Amyloid and Relevance to Amyloidogenesis and Alzheimer's Disease (AD).

Y Zhao, P Dua, W J Lukiw

Open access · hybridAbstract read
In one paragraph

Article in Journal of Alzheimer's disease & Parkinsonism, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 137 citations in OpenAlex.

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  14. Protective Effects of Heat-KilledJournal of microbiology and biotechnology · 2024
    Article
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  18. Dysbiosis and Alzheimer's disease: role of probiotics, prebiotics and synbiotics.Naunyn-Schmiedeberg's archives of pharmacology · 2023
    Review
  19. Review
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Y ZhaoLSU Neuroscience Center, Louisiana State University Health Sciences Center, 2020 Gravier Street, New Orleans LA 70112 USA ; Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans LA 70112 USA.
P DuaDepartment of Health Information Management, Louisiana State University Ruston LA 71270 USA.
W J LukiwLSU Neuroscience Center, Louisiana State University Health Sciences Center, 2020 Gravier Street, New Orleans LA 70112 USA ; Department of Ophthalmology, Louisiana State University Health Sciences Center, 533 Bolivar Street, New Orleans LA 70112 USA ; Department of Neurology, Louisiana State University Health Sciences Center, 1542 Tulane Avenue, New Orleans LA 70112 USA.
Louisiana State University Health Sciences Center New Orleans · US

Funding

UC Irvine Alzheimer's Disease Research Center Induced Pluripotent Stem Cell CoreP50AG016573 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI LAFERLA, FRANK M · 2000 to 2019
$37.0M
OCULAR HSV: LATENCY, REACTIVATION, &RECURRENCER01EY006311 · NEI · LSU HEALTH SCIENCES CENTER · PI HILL, JAMES M · 1985 to 2012
$5.3M
Multiphoton ConfocalP30GM103340 · NIGMS · LSU HEALTH SCIENCES CENTER · PI BAZAN, NICOLAS G. · 2012 to 2016
$5.1M
microRNA (miRNA) signaling in Alzheimer's disease(AD)R01AG038834 · NIA · LSU HEALTH SCIENCES CENTER · PI BAZAN, NICOLAS G. · 2011 to 2020
$3.3M
Gene Expression in Alzheimer's DiseaseR01AG018031 · NIA · LSU HEALTH SCIENCES CENTER · PI LUKIW, WALTER J · 2001 to 2006
$1.4M
NEI NIH HHS R01 EY006311NIA NIH HHS P50 AG016573NIA NIH HHS R01 AG018031NIA NIH HHS R01 AG038834NIGMS NIH HHS P30 GM103340
6 · The paper itself

Abstract

Since the inception of the human microbiome project (HMP) by the US National Institutes of Health (NIH) in 2007 there has been a keen resurgence in our recognition of the human microbiome and its contribution to development, immunity, neurophysiology, metabolic and nutritive support to central nervous system (CNS) health and disease. What is not generally appreciated is that (i) the ~10

Indexed as

Alzheimer’s disease (AD)Beta amyloid precursor protein (βAPP)Congo Red (CR)Curli fibersHologenomeInflammationInnate-immunitySenile (amyloid) plaques (SP)Toll receptor type 2 (TLR2)

Identifiers

PMID25977840
PMCPMC4428612
OpenAlexW225152533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.