Evidence map›Paper›PMID 25977810›Full record

ArticleScientific data2015

The pediatric template of brain perfusion.

Brian B Avants, Jeffrey T Duda, Emily Kilroy, Kate Krasileva, Kay Jann, Benjamin T Kandel, Nicholas J Tustison, Lirong Yan, Mayank Jog, Robert Smith and 3 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  17. Developmental patterns of CBF and BOLD responses to visual stimulus.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Brian B AvantsDepartment of Radiology, University of Pennsylvania , Philadelphia, Pennsylvania 19104, USA.
Jeffrey T DudaDepartment of Radiology, University of Pennsylvania , Philadelphia, Pennsylvania 19104, USA.
Emily KilroyDepartment of Neurology, University of California , Los Angeles, California 90095, USA.
Kate KrasilevaDepartment of Neurology, University of California , Los Angeles, California 90095, USA.
Kay JannDepartment of Neurology, University of California , Los Angeles, California 90095, USA.
Benjamin T KandelDepartment of Radiology, University of Pennsylvania , Philadelphia, Pennsylvania 19104, USA.
Nicholas J TustisonDepartment of Radiology, University of Virginia , Charlottesville, Virginia 22904, USA.
Lirong YanDepartment of Neurology, University of California , Los Angeles, California 90095, USA.
Mayank JogDepartment of Neurology, University of California , Los Angeles, California 90095, USA.
Robert SmithDepartment of Neurology, University of California , Los Angeles, California 90095, USA.
Yi WangDepartment of Neurology, University of California , Los Angeles, California 90095, USA.
Mirella DaprettoDepartment of Neurology, University of California , Los Angeles, California 90095, USA.
Danny J J WangDepartment of Neurology, University of California , Los Angeles, California 90095, USA.

Funding

Pediatric Template of Brain PerfusionR01MH080892 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI WANG, DANNY JJ · 2009 to 2013
$3.3M
NIMH NIH HHS R01 MH080892NIMH NIH HHS R01-MH080892
6 · The paper itself

Abstract

Magnetic resonance imaging (MRI) captures the dynamics of brain development with multiple modalities that quantify both structure and function. These measurements may yield valuable insights into the neural patterns that mark healthy maturation or that identify early risk for psychiatric disorder. The Pediatric Template of Brain Perfusion (PTBP) is a free and public neuroimaging resource that will help accelerate the understanding of childhood brain development as seen through the lens of multiple modality neuroimaging and in relation to cognitive and environmental factors. The PTBP uses cross-sectional and longitudinal MRI to quantify cortex, white matter, resting state functional connectivity and brain perfusion, as measured by Arterial Spin Labeling (ASL), in 120 children 7-18 years of age. We describe the PTBP and show, as a demonstration of validity, that global summary measurements capture the trajectories that demarcate critical turning points in brain maturation. This novel resource will allow a more detailed understanding of the network-level, structural and functional landmarks that are obtained during normal adolescent brain development.

Indexed as

BrainMagnetic Resonance ImagingNeuroimagingAdolescentAdolescent DevelopmentAnatomy, Cross-SectionalChildChild DevelopmentHumansImage Processing, Computer-Assisted

Identifiers

PMID25977810
PMCPMC4413243

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.