ArticleNanoscale research letters2015
DNA-functionalized silicon nitride nanopores for sequence-specific recognition of DNA biosensor.
Article in Nanoscale research letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- The evolution of nanopore measurements: from biological out-of-plane pores to plastic in-plane pores.Lab on a chip · 2026Review
- Applications of Surface Plasmon Resonance for Advanced Studies Involving Nucleic Acids.RNA nanomed · 2024Article
- Achieving high hybridization density at DNA biosensor surfaces using branched spacer and click chemistry.RSC advances · 2023Article
- Silicon Nitride-Based Micro-Apertures Coated with Parylene for the Investigation of Pore Proteins Fused in Free-Standing Lipid Bilayers.Membranes · 2022Article
- Hybrid microchannel-solid state micropore device for fast and optical cell detection.RSC advances · 2020Article
- Small molecule electro-optical binding assay using nanopores.Nature communications · 2019Article
- Review
- Hydrogen Peroxide Sensing Based on Inner Surfaces Modification of Solid-State Nanopore.Nanoscale research letters · 2017Article
- Nanopore extended field-effect transistor for selective single-molecule biosensing.Nature communications · 2017Article
- Single Nanoparticle Translocation Through Chemically Modified Solid Nanopore.Nanoscale research letters · 2016Article
- A Nanofluidic Biosensor Based on Nanoreplica Molding Photonic Crystal.Nanoscale research letters · 2016Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanopores have been proven to be novel and versatile single-molecule sensors for individual unlabeled biopolymer detection and characterization. In the present study, a relatively large silicon nitride (Si3N4) nanopore with a diameter of approximately 60 nm was fabricated successfully using a focused Ga ion beam (FIB). We demonstrated a simple ex situ silanization procedure to control the size and functionality of solid-state nanopores. The presented results show that by varying the silanization time, it is possible to adjust the efficiency of probe molecule attachment, thus shrinking the pore to the chosen size, while introducing selective sensing probes. The functionalization of nanopores was verified by analysis of field-emission scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDS), and electrical measurements. Based on this study, we envision that the functionalized silicon nitride nanopores with the DNA probe might provide a biosensing platform for the detection and discrimination of a short single-stranded DNA oligomer of unknown sequences in the future.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.