ArticleScience (New York, N.Y.)2015
Social evolution. Genomic signatures of evolutionary transitions from solitary to group living.
Abstract readComparative Study
In one paragraph
Article in Science (New York, N.Y.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 176 papers, 1 of them a synthesis that pooled it.
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176citing papers in PubMed, 1 pooled it
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Who cites it
176 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-Analysis of Public RNA Sequencing Data Revealed Potential Key Genes Associated with Reproductive Division of Labor in Social Hymenoptera and Termites.International journal of molecular sciences · 2023Pooled it
- Genome Evolution in Social Insects.Genome biology and evolution · 2026Review
- Dynamic workforce modulation and foraging efficiency in Eusocial insect colonies.PLoS computational biology · 2026Article
- Transcription Factor Evolution Associated with Social Transitions in Blattodea.Journal of molecular evolution · 2026Article
- Genomic Insights Into the Evolution of Parental Care in Weevils.Genome biology and evolution · 2026Article
- Genome-Wide Identification of Transcriptional Start Sites and Candidate Enhancers Regulating Worker Metamorphosis inInsects · 2026Article
- Unmated Queens Show Worker-Like Behaviour and Gene Expression in Polygynous Colonies of the Ant Stigmatomma pallipes.Molecular ecology · 2026Article
- The Evolutionary and Ecological Consequences of Cooperation.The American naturalist · 2026Review
- The evolution of the immune system of bees is defined by conservation, expansions, and losses.BMC biology · 2026Article
- Regulatory RNA Patterns Associated with Bee Evolution Should Be Interpreted with Caution, but Correlational Studies Should Not Be Entirely Dismissed.Genome biology and evolution · 2026Article
- Genome Assemblies of the Daisy Gorteria diffusa Elucidate the Molecular-Genomic Basis of Pollination by Sexual Deception.Genome biology and evolution · 2026Article
- Fraternal cooperation of hierarchical cancer parallels metazoan multicellularity and eusociality.Biological reviews of the Cambridge Philosophical Society · 2026Review
- The Weak Worker Hypothesis: a new framework for understanding division of labour in social insects.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Cryptocercus Genomes Expand Knowledge of Adaptations to Xylophagy and Termite Sociality.Genome biology and evolution · 2026Article
- Evolutionary Transitions in Social Behavior are Associated With Convergent and Partially Reversible Expansions of Transcription Factor Binding Sites.Genome biology and evolution · 2026Article
- Retroelement expansions underlie genome evolution in stingless bees.BMC genomics · 2026Article
- The Evolution of Bees: Insights from 'Omic Studies.Genome biology and evolution · 2026Review
- A Chromosome-Level Genome Assembly and Resequencing Data Reveal Low DNA Methylation and Reduced Diversity in the Solitary Bee Pollinator Osmia cornuta.Genome biology and evolution · 2026Article
- Distinct colony niches shape associated microbiotas in Neotropical stingless bees.Genetics and molecular biology · 2026Article
- The fru gene specifies male cooperative behaviors in honeybee colonies.Nature communications · 2025Article
116 more citing papers are in PubMed but not listed here.
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Authors and funding
52 authors.
Karen M KapheimCarl R. WoeseInstitute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Department of Entomology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Department of Biology, Utah State University, Logan, UT 84322, USA. karen.kapheim@usu.edu wangj@genomics.org.cn generobi@illinois.edu zhanggj@genomics.org.cn.
Hailin PanChina National GeneBank, BGI-Shenzhen, Shenzhen, 518083, China.
Cai LiChina National GeneBank, BGI-Shenzhen, Shenzhen, 518083, China. Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, 1350, Denmark.
Steven L SalzbergDepartments of Biomedical Engineering, Computer Science, and Biostatistics, Johns Hopkins University, Baltimore, MD 21218, USA. Center for Computational Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Daniela PuiuCenter for Computational Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Tanja MagocCenter for Computational Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Hugh M RobertsonCarl R. WoeseInstitute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Department of Entomology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Matthew E HudsonCarl R. WoeseInstitute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Department of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Aarti VenkatCarl R. WoeseInstitute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Department of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.
Brielle J FischmanCarl R. WoeseInstitute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Program in Ecology and Evolutionary Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Department of Biology, Hobart and William Smith Colleges, Geneva, NY 14456, USA.
Alvaro HernandezRoy J. Carver Biotechnology Center, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Mark YandellDepartment of Human Genetics, Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA. USTAR Center for Genetic Discovery, University of Utah, Salt Lake City, UT 84112, USA.
Daniel EnceDepartment of Human Genetics, Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA.
Carson HoltDepartment of Human Genetics, Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA. USTAR Center for Genetic Discovery, University of Utah, Salt Lake City, UT 84112, USA.
George D YocumU.S. Department of Agriculture-Agricultural Research Service (USDA-ARS) Red River Valley Agricultural Research Center, Biosciences Research Laboratory, Fargo, ND 58102, USA.
William P KempU.S. Department of Agriculture-Agricultural Research Service (USDA-ARS) Red River Valley Agricultural Research Center, Biosciences Research Laboratory, Fargo, ND 58102, USA.
Jordi BoschCenter for Ecological Research and Forestry Applications (CREAF), Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain.
Robert M WaterhouseDepartment of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, Switzerland. Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland. Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Evgeny M ZdobnovDepartment of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, Switzerland. Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland.
Eckart StolleInstitute of Biology, Department Zoology, Martin-Luther-University Halle-Wittenberg, Hoher Weg 4, D-06099 Halle (Saale), Germany. Queen Mary University of London, School of Biological and Chemical Sciences Organismal Biology Research Group, London E1 4NS, UK.
F Bernhard KrausInstitute of Biology, Department Zoology, Martin-Luther-University Halle-Wittenberg, Hoher Weg 4, D-06099 Halle (Saale), Germany. Department of Laboratory Medicine, University Hospital Halle, Ernst Grube Strasse 40, D-06120 Halle (Saale), Germany.
Sophie HelbingInstitute of Biology, Department Zoology, Martin-Luther-University Halle-Wittenberg, Hoher Weg 4, D-06099 Halle (Saale), Germany.
Robin F A MoritzInstitute of Biology, Department Zoology, Martin-Luther-University Halle-Wittenberg, Hoher Weg 4, D-06099 Halle (Saale), Germany. German Centre for Integrative Biodiversity Research (iDiv), Halle-Jena-Leipzig, 04103 Leipzig, Germany.
Karl M GlastadSchool of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Brendan G HuntDepartment of Entomology, University of Georgia, Griffin, GA 30223, USA.
Michael A D GoodismanSchool of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Frank HauserCenter for Functional and Comparative Insect Genomics, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
Cornelis J P GrimmelikhuijzenCenter for Functional and Comparative Insect Genomics, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
Daniel Guariz PinheiroDepartamento de Biologia, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, 14040-901 Ribeirão Preto, SP, Brazil. Departamento de Tecnologia, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (UNESP), 14884-900 Jaboticabal, SP, Brazil.
Francis Morais Franco NunesDepartamento de Genética e Evolução, Centro de Ciências Biológicas e da Saúde, Universidade Federal de São Carlos, 13565-905 São Carlos, SP, Brazil.
Michelle Prioli Miranda SoaresDepartamento de Biologia, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, 14040-901 Ribeirão Preto, SP, Brazil.
Érica Donato TanakaDepartamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, 14049-900 Ribeirão Preto, SP, Brazil.
Zilá Luz Paulino SimõesDepartamento de Biologia, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, 14040-901 Ribeirão Preto, SP, Brazil.
Klaus HartfelderDepartamento de Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, 14049-900 Ribeirão Preto, SP, Brazil.
Jay D EvansUSDA-ARS Bee Research Lab, Beltsville, MD 20705 USA.
Seth M BarribeauDepartment of Biology, East Carolina University, Greenville, NC 27858, USA.
Reed M JohnsonDepartment of Entomology, Ohio Agricultural Research and Development Center, Ohio State University, Wooster, OH 44691, USA.
Jonathan H MasseyDepartment of Entomology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Bruce R SoutheyDepartment of Animal Sciences, University of Illinois, Urbana, IL 61801, USA.
Martin HasselmannDepartment of Population Genomics, Institute of Animal Husbandry and Animal Breeding, University of Hohenheim, Germany.
Daniel HamacherDepartment of Population Genomics, Institute of Animal Husbandry and Animal Breeding, University of Hohenheim, Germany.
Matthias BiewerDepartment of Population Genomics, Institute of Animal Husbandry and Animal Breeding, University of Hohenheim, Germany.
Clement F KentDepartment of Biology, York University, Toronto, ON M3J 1P3, Canada. Janelia Farm Research Campus, Howard Hughes Medical Institue, Ashburn, VA 20147, USA.
Amro ZayedDepartment of Biology, York University, Toronto, ON M3J 1P3, Canada.
Charles BlattiCarl R. WoeseInstitute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Saurabh SinhaCarl R. WoeseInstitute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
J Spencer JohnstonDepartment of Entomology, Texas A&M University, College Station, TX 77843, USA.
Shawn J HanrahanDepartment of Entomology, Texas A&M University, College Station, TX 77843, USA.
Sarah D KocherDepartment of Organismic and Evolutionary Biology, Museum of Comparative Zoology, Harvard University, Cambridge, MA 02138, USA.
Jun WangChina National GeneBank, BGI-Shenzhen, Shenzhen, 518083, China. Department of Biology, University of Copenhagen, 2200 Copenhagen, Denmark. Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Macau University of Science and Technology, Avenida Wai long, Taipa, Macau 999078, China. Department of Medicine, University of Hong Kong, Hong Kong. karen.kapheim@usu.edu wangj@genomics.org.cn generobi@illinois.edu zhanggj@genomics.org.cn.
Gene E RobinsonCarl R. WoeseInstitute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Center for Advanced Study Professor in Entomology and Neuroscience, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. karen.kapheim@usu.edu wangj@genomics.org.cn generobi@illinois.edu zhanggj@genomics.org.cn.
Guojie ZhangChina National GeneBank, BGI-Shenzhen, Shenzhen, 518083, China. Centre for Social Evolution, Department of Biology, Universitetsparken 15, University of Copenhagen, DK-2100 Copenhagen, Denmark. karen.kapheim@usu.edu wangj@genomics.org.cn generobi@illinois.edu zhanggj@genomics.org.cn.
Funding
Johnny Bee Good: Bees as Models to Study the Hijacking of the Reward SystemDP1OD006416 · OD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI ROBINSON, GENE E · 2009 to 2011
$2.4MHoward Hughes Medical InstituteNIH HHS DP1 OD006416
Abstract
The evolution of eusociality is one of the major transitions in evolution, but the underlying genomic changes are unknown. We compared the genomes of 10 bee species that vary in social complexity, representing multiple independent transitions in social evolution, and report three major findings. First, many important genes show evidence of neutral evolution as a consequence of relaxed selection with increasing social complexity. Second, there is no single road map to eusociality; independent evolutionary transitions in sociality have independent genetic underpinnings. Third, though clearly independent in detail, these transitions do have similar general features, including an increase in constrained protein evolution accompanied by increases in the potential for gene regulation and decreases in diversity and abundance of transposable elements. Eusociality may arise through different mechanisms each time, but would likely always involve an increase in the complexity of gene networks.
Indexed as
Evolution, MolecularGenetic DriftSocial BehaviorTranscriptomeAmino-Acid N-AcetyltransferaseAnimalsBeesDNA Transposable ElementsGene Expression RegulationGene Regulatory NetworksGenome, InsectPhylogenySelection, GeneticTranscription FactorsAmino-Acid N-AcetyltransferaseDNA Transposable ElementsTranscription Factors
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