Evidence map›Paper›PMID 25977205›Full record

ArticleDrug and alcohol dependence2015

Addiction and treatment experiences among active methamphetamine users recruited from a township community in Cape Town, South Africa: A mixed-methods study.

Christina S Meade, Sheri L Towe, Melissa H Watt, Ryan R Lion, Bronwyn Myers, Donald Skinner, Stephen Kimani, Desiree Pieterse

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Smoked drug use in patients with TB is associated with higher bacterial burden.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  7. COVID 19-impact on substance use treatment utilization and provision in South Africa.Substance abuse treatment, prevention, and policy · 2022
    Article
  8. Article
  9. Article
  10. Methamphetamine Dysregulation of the Central Nervous System and Peripheral Immunity.The Journal of pharmacology and experimental therapeutics · 2021
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. The Opioid Epidemic in Africa And Its Impact.Current addiction reports · 2018
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christina S MeadeDuke University School of Medicine, Department of Psychiatry & Behavioral Sciences and Duke Global Health Institute, Box 90519, Durham, NC 27708, USA. Electronic address: christina.meade@duke.edu.
Sheri L ToweDuke University School of Medicine, Department of Psychiatry & Behavioral Sciences and Duke Global Health Institute, Box 90519, Durham, NC 27708, USA. Electronic address: sheri.towe@duke.edu.
Melissa H WattDuke University, Duke Global Health Institute, Box 90519, Durham, NC 27708, USA. Electronic address: melissa.watt@duke.edu.
Ryan R LionDuke University, Duke Global Health Institute, Box 90519, Durham, NC 27708, USA. Electronic address: ryan.lion@duke.edu.
Bronwyn MyersAlcohol, Tobacco and Other Drug Research Unit, South African Medical Research Council, Box 19070, Tygerberg 7505, South Africa. Electronic address: bronwyn.myers@mrc.ac.za.
Donald SkinnerStellenbosch University, Faculty of Medicine and Health Sciences, Box 19063, Tygerberg 7505, South Africa. Electronic address: dskinner@sun.ac.za.
Stephen KimaniDuke University, Duke Global Health Institute, Box 90519, Durham, NC 27708, USA. Electronic address: stephen.kimani@duke.edu.
Desiree PieterseStellenbosch University, Faculty of Medicine and Health Sciences, Box 19063, Tygerberg 7505, South Africa. Electronic address: dpieterse2014@gmail.com.

Funding

Ruth L. Kirschstein National Research Service Award (NRSA)- T32T32AI007392 · NIAID · DUKE UNIVERSITY · PI Amy Lynn Corneli, Guido Ferrari · 1990 to 2026
$9.8M
Neurobehavioral and fMRI Research in HIV Infection and Cocaine DependenceK23DA028660 · NIDA · DUKE UNIVERSITY · PI MEADE, CHRISTINA S · 2010 to 2014
$825k
HIV risk behaviors among methamphetamine users in Cape Town, South AfricaR03DA033828 · NIDA · DUKE UNIVERSITY · PI MEADE, CHRISTINA S · 2012 to 2013
$333k
NIAID NIH HHS T32 AI007392NIAID NIH HHS T32-AI007392NIDA NIH HHS K23 DA028660NIDA NIH HHS K23-DA028660NIDA NIH HHS R03 DA033828NIDA NIH HHS R03-DA033828
6 · The paper itself

Abstract

backgroundSince 2000, there has been a dramatic increase in methamphetamine use in South Africa, but little is known about the experiences of out-of-treatment users. This mixed-methods study describes the substance use histories, addiction symptoms, and treatment experiences of a community-recruited sample of methamphetamine users in Cape Town.

methodsUsing respondent driven sampling, 360 methamphetamine users (44% female) completed structured clinical interviews to assess substance abuse and treatment history and computerized surveys to assess drug-related risks. A sub-sample of 30 participants completed in-depth interviews to qualitatively explore experiences with methamphetamine use and drug treatment.

resultsParticipants had used methamphetamine for an average of 7.06 years (SD=3.64). They reported using methamphetamine on an average of 23.49 of the past 30 days (SD=8.90); 60% used daily. The majority (90%) met ICD-10 criteria for dependence, and many reported severe social, financial, and legal consequences. While only 10% had ever received drug treatment, 90% reported that they wanted treatment. In the qualitative interviews, participants reported multiple barriers to treatment, including beliefs that treatment is ineffective and relapse is inevitable in their social context. They also identified important motivators, including desires to be drug free and improve family functioning.

conclusionThis study yields valuable information to more effectively respond to emerging methamphetamine epidemics in South Africa and other low- and middle-income countries. Interventions to increase uptake of evidence-based services must actively seek out drug users and build motivation for treatment, and offer continuing care services to prevent relapse. Community education campaigns are also needed.

Indexed as

MethamphetamineAdolescentAdultAgedAmphetamine-Related DisordersDrug UsersFemaleHealth SurveysHumansMaleMiddle AgedMotivationPatient Acceptance of Health CareSmokingSocioeconomic FactorsSouth AfricaMethamphetamineAddictionDrug abuseMethamphetamineSouth AfricaSubstance abuse treatment

Identifiers

PMID25977205
PMCPMC4498803

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.