ArticleJournal of hematology & oncology2015
The impact of taxane-based preoperative chemotherapy in gastroesophageal signet ring cell adenocarcinomas.
Article in Journal of hematology & oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- A Rare Case of Primary Gastric Signet Ring Cell Carcinoma: a Review of Guidelines for the Management of Gastric Cancer.Indian journal of surgical oncology · 2024Article
- Current trends in perioperative treatment of resectable gastric cancer.World journal of gastrointestinal surgery · 2023Review
- Survival analysis and individualized prediction of survival benefit for pancreatic signet ring cell carcinoma: a population study based on the SEER database.BMC gastroenterology · 2023Article
- Neoadjuvant chemotherapy outcome with taxane-based versus non-taxane protocols in gastric cancer.Journal of education and health promotion · 2023Article
- Molecular profiling of signet-ring-cell carcinoma (SRCC) from the stomach and colon reveals potential new therapeutic targets.Oncogene · 2022Article
- Signet-ring cell carcinoma of the duodenal bulb presenting with gastrointestinal hemorrhage: a case report and literature review.BMC gastroenterology · 2022Review
- Impact of neoadjuvant therapy followed by laparoscopic radical gastrectomy with D2 lymph node dissection in Western population: A multi-institutional propensity score-matched study.Journal of surgical oncology · 2021Article
- Prognostic Nomograms for Nonelderly Adults with Gastric Signet Ring Cell Carcinoma.BioMed research international · 2021Article
- Article
- Neoadjuvant chemotherapyWorld journal of gastroenterology · 2020Article
- State of the art for gastric signet ring cell carcinoma: from classification, prognosis, and genomic characteristics to specified treatments.Cancer management and research · 2019Review
- Efficacy of a docetaxel-5FU-oxaliplatin regimen (TEFOX) in first-line treatment of advanced gastric signet ring cell carcinoma: an AGEO multicentre study.British journal of cancer · 2018Article
- Signet-ring cell carcinoma of the stomach: Impact on prognosis and specific therapeutic challenge.World journal of gastroenterology · 2015Review
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The benefit of preoperative chemotherapy in resectable gastroesophageal adenocarcinomas was not observed in signet ring cell subtype. However, the potential interest of taxane-based preoperative chemotherapy on this subtype is still an unresolved issue. Nineteen patients with localized signet ring cell adenocarcinomas received taxane-based regimens, and 17 patients underwent surgery. Complete resection was achieved in 80 %, and median overall survival was 40.8 months (95 % confidence interval (CI), 20.2-not reached). Even though one patient achieved a complete pathological response, seven patients had an upstaging of their tumors at surgery. The potential benefits of taxane-based chemotherapy seem to be limited to a reduced number of patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.