Evidence map›Paper›PMID 25975717›Full record

ArticleBMC cancer2015

Clinical characteristics of narrow-band imaging of oral erythroplakia and its correlation with pathology.

Shih-Wei Yang, Yun-Shien Lee, Liang-Che Chang, Cheng-Cheng Hwang, Cheng-Ming Luo, Tai-An Chen

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Narrow Band Imaging: An Effective and Early Diagnostic Tool in Diagnosis of Oral Malignant Lesions.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2019
    Article
  11. Observational
  12. Article
  13. The diagnostic value of narrow band imaging in different oral and oropharyngeal subsites.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shih-Wei YangDepartment of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Keelung; No. 222, Mai Chin Road, Keelung, 204, Taiwan. sweeyang@gmail.com.
Yun-Shien LeeGenomic Medicine Research Core Laboratory, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan. bojack@mail.mcu.edu.tw.
Liang-Che ChangSchool of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan. lc2008@cgmh.org.tw.
Cheng-Cheng HwangSchool of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan. rrooyyaa@cgmh.org.tw.
Cheng-Ming LuoDepartment of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Keelung; No. 222, Mai Chin Road, Keelung, 204, Taiwan. lcm3647@gmail.com.
Tai-An ChenDepartment of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Keelung; No. 222, Mai Chin Road, Keelung, 204, Taiwan. anmaka@ms15.hinet.net.
Chang Gung University · TWChang Gung University of Science and Technology · TWMing Chuan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo analyze the clinical application of endoscope with narrow-band imaging (NBI) system in detecting high-grade dysplasia, carcinoma in situ, and carcinoma in oral erythroplakia.

methodsThe demographic, histopathological data, and NBI vasculature architectures of patients receiving surgical intervention for oral erythroplakia were retrospectively reviewed and analyzed statistically.

resultsA total of 72 patients, including 66 males and 6 females, with mean age of 54.6 ± 11.2 years, were enrolled. The odds ratio of detecting high-grade dysplasia, carcinoma in situ, and carcinoma by twisted elongated morphology and destructive pattern of intraepithelial microvasculature was 15.46 (confidence interval 95%: 3.81-72.84), and the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 80.95%, 78.43%, 60.71%, 90.91%, and 79.17%, respectively, which were significantly better than other two established NBI criteria (p < 0.001).

conclusionsTwisted, elongated, and destructive patterns of intraepithelial papillary capillary loop of NBI images are indicators for high-grade dysplasia, carcinoma in situ, and invasive carcinoma in oral erythroplakia.

Indexed as

AdultAgedErythroplasiaFemaleHumansMaleMiddle AgedMouth NeoplasmsNarrow Band ImagingRetrospective Studies

Identifiers

PMID25975717
PMCPMC4434519
OpenAlexW1524372295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.