ReviewGut2015
Emerging optical methods for surveillance of Barrett's oesophagus.
Review in Gut, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- PARP1-targeted fluorescence molecular endoscopy as novel tool for early detection of esophageal dysplasia and adenocarcinoma.Journal of experimental & clinical cancer research : CR · 2024Article
- A novel endoscopy image fusion system: combine white light imaging and compound band imaging.International journal of computer assisted radiology and surgery · 2024Article
- Hybrid confocal Raman endomicroscopy for morpho-chemical tissue characterization.Biomedical optics express · 2022Article
- Advanced endoscopic imaging for detecting and guiding therapy of early neoplasias of the esophagus.Annals of the New York Academy of Sciences · 2020Review
- Is Malignant Potential of Barrett's Esophagus Predictable by Endoscopy Findings?Life (Basel, Switzerland) · 2020Review
- Use of Fluorescent Dyes in Endoscopy and Diagnostic Investigation.Visceral medicine · 2020Review
- Quantitative phase and polarization imaging through an optical fiber applied to detection of early esophageal tumorigenesis.Journal of biomedical optics · 2019Article
- CAESNet: Convolutional AutoEncoder based Semi-supervised Network for improving multiclass classification of endomicroscopic images.Journal of the American Medical Informatics Association : JAMIA · 2019Article
- A roadmap for the clinical implementation of optical-imaging biomarkers.Nature biomedical engineering · 2019Review
- A clinically translatable hyperspectral endoscopy (HySE) system for imaging the gastrointestinal tract.Nature communications · 2019Article
- Quantitative evaluation of comb-structure correction methods for multispectral fibrescopic imaging.Scientific reports · 2018Article
- Bimodal reflectance and fluorescence multispectral endoscopy based on spectrally resolving detector arrays.Journal of biomedical optics · 2018Article
- Point-Counterpoint: Screening and Surveillance for Barrett's Esophagus, Is It Worthwhile?Digestive diseases and sciences · 2018Review
- In-vivo optical imaging in head and neck oncology: basic principles, clinical applications and future directions.International journal of oral science · 2018Review
- Active thermodynamic contrast imaging for label-free tumor detection in a murine xenograft tumor model.Biomedical optics express · 2017Article
- Identification and validation of FGFR2 peptide for detection of early Barrett's neoplasia.Oncotarget · 2017Article
- Shining a White Light on Barrett's Esophagus: What Does the BING Classification Bring?Digestive diseases and sciences · 2017Article
- Plant Lectins as Medical Tools against Digestive System Cancers.International journal of molecular sciences · 2017Review
- Beyond Dysplasia Grade: The Role of Biomarkers in Stratifying Risk.Gastrointestinal endoscopy clinics of North America · 2017Review
- Fluorescence hyperspectral imaging (fHSI) using a spectrally resolved detector array.Journal of biophotonics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The rapid rise in incidence of oesophageal adenocarcinoma has motivated the need for improved methods for surveillance of Barrett's oesophagus. Early neoplasia is flat in morphology and patchy in distribution and is difficult to detect with conventional white light endoscopy (WLE). Light offers numerous advantages for rapidly visualising the oesophagus, and advanced optical methods are being developed for wide-field and cross-sectional imaging to guide tissue biopsy and stage early neoplasia, respectively. We review key features of these promising methods and address their potential to improve detection of Barrett's neoplasia. The clinical performance of key advanced imaging technologies is reviewed, including (1) wide-field methods, such as high-definition WLE, chromoendoscopy, narrow-band imaging, autofluorescence and trimodal imaging and (2) cross-sectional techniques, such as optical coherence tomography, optical frequency domain imaging and confocal laser endomicroscopy. Some of these instruments are being adapted for molecular imaging to detect specific biological targets that are overexpressed in Barrett's neoplasia. Gene expression profiles are being used to identify early targets that appear before morphological changes can be visualised with white light. These targets are detected in vivo using exogenous probes, such as lectins, peptides, antibodies, affibodies and activatable enzymes that are labelled with fluorescence dyes to produce high contrast images. This emerging approach has potential to provide a 'red flag' to identify regions of premalignant mucosa, outline disease margins and guide therapy based on the underlying molecular mechanisms of cancer progression.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.