ArticleCancer2015
Male-female patient differences in the association between end-of-life discussions and receipt of intensive care near death.
Article in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 4 syntheses or guidelines pooled it, 130 citations in OpenAlex.
- Sex-related differences in end-of-life decision-making in patients with traumatic brain injury: a systematic review and meta-analysis.BMC palliative care · 2026Pooled it
- How well is the female population represented in clinical trials with infusion therapies for Parkinson's disease? A systematic review and metanalysis.European journal of neurology · 2025Pooled it
- Associations Among End-of-Life Discussions, Health-Care Utilization, and Costs in Persons With Advanced Cancer: A Systematic Review.The American journal of hospice & palliative care · 2019Pooled it
- End-of-life care preferences for people with advanced cancer and their families in intensive care units: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Pooled it
- End-of-Life Preferences: A Randomized Trial of Framing Comfort Care as Refusal of Treatment in the Context of COVID-19.Medical decision making : an international journal of the Society for Medical Decision Making · 2023Trial
- Perceptions of Need for Palliative Care in Recently Hospitalized Patients With Systolic Heart Failure.Journal of pain and symptom management · 2021Trial
- Preference for Palliative Care in Cancer Patients: Are Men and Women Alike?Journal of pain and symptom management · 2018Trial
- Older patients and intensive care: factors that influence patients decisions on life sustaining measures.BMC geriatrics · 2026Article
- Hospice referral patterns in India during COVID-19: A retrospective study on advanced cancer patients.BMC palliative care · 2026Article
- Timing matters: sex differences in treatment limitation decisions in intensive care.Critical care (London, England) · 2026Article
- Sex and Racial/Ethnic Differences in End-of-Life Care in Texan Medicare Colorectal Cancer Decedents.The American journal of hospice & palliative care · 2026Article
- Diversity-sensitive palliative and hospice care in Germany - awareness, attitudes, and measures taken by service providers.BMC palliative care · 2026Article
- Age and sex-based differences in therapy preferences among patients with cancer: evidence from a novel therapy preference scale.Ecancermedicalscience · 2026Article
- Article
- Sex and Racial/Ethnic Differences in End-of-Life Care Preferences in Persons with Parkinson's Disease and Related Disorders.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Sex differences in advance directives and their clinical translation among critically ill adults: results from the ADVISE study.Annals of intensive care · 2025Article
- Acute Care Use and Prognosis in Older Adults Presenting to the Emergency Department.Journal of pain and symptom management · 2025Article
- Gender differences in palliative care needs among Swedish cancer patients prior to specialist palliative care referral.Acta oncologica (Stockholm, Sweden) · 2025Article
- Temporal Trends in Mortality Location Among Patients With Intrahepatic Cholangiocarcinoma in the USA: A Retrospective Observational Analysis of National Center for Health Statistics Mortality Data.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Demographic Factors and Aortic Stenosis-Related Death Locations: A Cross-Sectional Analysis.Journal of clinical medicine · 2025Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPatient gender plays a significant role in patient-physician communication, patients' understanding of illness, and the aggressiveness of end-of-life (EoL) care. However, little is known about the extent to which gender differences in the effects of EoL discussions on EoL care contribute to gender differences in EoL care. The current study was aimed at determining whether gender differences exist in the receipt of intensive care unit (ICU) care near death and in the association between EoL discussions and the receipt of EoL ICU care.
methodsThis was a multisite, prospective cohort study of patients (n = 353) with metastatic cancers who were identified as terminally ill at study enrollment and were interviewed at a median of 4.1 months before their deaths. Postmortem chart reviews and caregiver interviews documented ICU stays in the last week of life.
resultsPatients who received ICU care at the EoL were more likely to be male than those who did not (73% vs 52%, P = .02). After adjustments for potential confounders, male patients reporting an EoL discussion were less likely to have an ICU stay in the last week of life than male patients with no EoL discussion (adjusted odds ratio, 0.26, 95% confidence interval, 0.07-0.91; P = .04). There was no association between EoL discussions and ICU stays near death among female patients.
conclusionsMen with advanced cancers are more likely than women to receive aggressive, nonbeneficial ICU care near death. Gender differences in the effects of EoL discussions on EoL care likely contribute to and may even explain gender differences in the receipt of ICU care in the last week of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.