Evidence map›Paper›PMID 25974328›Full record

ArticleClinical and translational science2015

Culturally Competent Strategies for Recruitment and Retention of African American Populations into Clinical Trials.

Jane Otado, John Kwagyan, Diana Edwards, Alice Ukaegbu, Faun Rockcliffe, Nana Osafo

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and translational science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 9 pooled it
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 9 syntheses or guidelines pooled it, 240 citations in OpenAlex.

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  9. Retention of Ethnic Participants in Longitudinal Studies.Journal of immigrant and minority health · 2018
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  11. Randomized Comparison of Online Motivational Themes in Clinical Trial Recruitment.Circulation. Cardiovascular quality and outcomes · 2025
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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jane OtadoGeorgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS), Howard University, College of Medicine, Washington, District of Columbia, USA.
John KwagyanGeorgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS), Howard University, College of Medicine, Washington, District of Columbia, USA.
Diana EdwardsGeorgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS), Howard University, College of Medicine, Washington, District of Columbia, USA.
Alice UkaegbuGeorgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS), Howard University, College of Medicine, Washington, District of Columbia, USA.
Faun RockcliffeGeorgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS), Howard University, College of Medicine, Washington, District of Columbia, USA.
Nana OsafoGeorgetown-Howard Universities Center for Clinical and Translational Science (GHUCCTS), Howard University, College of Medicine, Washington, District of Columbia, USA.
Howard University · US

Funding

Maternal Morbidity and Mortality: Risk Factors, Early Detection and Personalized InterventionUL1TR001409 · NCATS · GEORGETOWN UNIVERSITY · PI GONDRE-LEWIS, MARJORIE C, MELLMAN, THOMAS A · 2015 to 2024
$37.8M
Georgetown-Howard Universities Center for Clinical and Translational Science (GHUUL1TR000101 · NCATS · GEORGETOWN UNIVERSITY · PI MELLMAN, THOMAS A, VERBALIS, JOSEPH G · 2012 to 2015
$19.3M
PROTEOMICS CORE FACILITYG12MD007597 · NIMHD · HOWARD UNIVERSITY · PI SOUTHERLAND, WILLIAM M. · 2012 to 2018
$14.8M
Georgetown-Howard Universities Center for Clinical and Translational Science (GHUUL1RR031975 · NCRR · GEORGETOWN UNIVERSITY · PI MELLMAN, THOMAS A, VERBALIS, JOSEPH G · 2010 to 2011
$14.6M
NCATS NIH HHS UL1 TR000101NCATS NIH HHS UL1TR000101NCATS NIH HHS UL1 TR001409NCRR NIH HHS UL1 RR031975NCRR NIH HHS UL1RR031975NIMHD NIH HHS G12 MD007597NIMHD NIH HHS G12MD007597
6 · The paper itself

Abstract

purposeTo identify successful recruitment strategies, challenges and best practices for researchers to engage African American communities in clinical studies taken into consideration target participants' culture and context.

methodsWe reviewed 50 studies conducted from 2001 to 2012 at an inner-city research center to determine the type, duration, anticipated enrollments and actual enrollments. Survey was sent to study coordinators to obtain data on recruitment and retention strategies, challenges and dropout rates. We also interviewed 25 study coordinators on challenges and strategies.

resultsOf the 50 studies, 24 had completed recruitment at the time of this report. The completed studies achieved a median recruitment rate of 88% (range: 50-110). Successful recruitment and retention strategies included: field-based strategy and snowballing. Major barriers were: distrust, compensation, education disadvantage, lack of interest, and inability to have study partner. Strategies to reduce barriers included providing informational sessions, disseminating newsletters about study outcomes. Best practices include being culturally sensitive including demonstrating a caring attitude and being responsive to participants needs.

conclusionsCultural competence is critical in order to design and implement successful recruitment strategies in this population. Research teams should consist of multiethnic staff, involve the community, demonstrate trust and deliver concise education of the research endeavor.

Indexed as

Cultural CompetencyPatient SelectionResearch SubjectsAttitude of Health PersonnelBlack or African AmericanClinical Trials as TopicCommunicationHealth Knowledge, Attitudes, PracticeHumansPatient DropoutsResearch PersonnelRetrospective StudiesSample SizeSurveys and QuestionnairesUnited StatesAfrican Americansclinical trialscultural competencyminoritiesrecruitment and retention strategiesunderrepresented minorities

Identifiers

PMID25974328
PMCPMC4626379
OpenAlexW2158685593

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.