ArticlePhysics in medicine and biology2015
The dynamic deformation of a layered viscoelastic medium under surface excitation.
Article in Physics in medicine and biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026Review
- Nanobomb optical coherence elastography in multilayered phantoms.Biomedical optics express · 2023Article
- Article
- Introduction to optical coherence elastography: tutorial.Journal of the Optical Society of America. A, Optics, image science, and vision · 2022Article
- Wave-based optical coherence elastography: The 10-year perspective.Progress in biomedical engineering (Bristol, England) · 2022Article
- Layer-specific ultrasound elastography using a multi-layered shear wave dispersion model for assessing the viscoelastic properties.Physics in medicine and biology · 2021Article
- Assessing colitisQuantitative imaging in medicine and surgery · 2019Article
- Optical coherence elastography of cold cataract in porcine lens.Journal of biomedical optics · 2019Article
- Assessing the biomechanical properties of the porcine crystalline lens as a function of intraocular pressure with optical coherence elastography.Biomedical optics express · 2018Article
- Noninvasive assessment of age-related stiffness of crystalline lenses in a rabbit model using ultrasound elastography.Biomedical engineering online · 2018Article
- Optical coherence elastography for evaluating customized riboflavin/UV-A corneal collagen crosslinking.Journal of biomedical optics · 2017Article
- The impact of intraocular pressure on elastic wave velocity estimates in the crystalline lens.Physics in medicine and biology · 2017Article
- Optical coherence elastography - OCT at work in tissue biomechanics [Invited].Biomedical optics express · 2017Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
In this study the dynamic behavior of a layered viscoelastic medium in response to the harmonic and impulsive acoustic radiation force applied to its surface was investigated both theoretically and experimentally. An analytical solution for a layered viscoelastic compressible medium in frequency and time domains was obtained using the Hankel transform. A special incompressible case was considered to model soft biological tissues. To verify our theoretical model, experiments were performed using tissue-like gel-based phantoms with varying mechanical properties. A 3.5 MHz single-element focused ultrasound transducer was used to apply the radiation force at the surface of the phantoms. A phase-sensitive optical coherence tomography system was used to track the displacements of the phantom surface. Theoretically predicted displacements were compared with experimental measurements. The role of the depth dependence of the elastic properties of a medium in its response to an acoustic pulse at the surface was studied. It was shown that the low-frequency vibrations at the surface are more sensitive to the deep layers than high-frequency ones. Therefore, the proposed model in combination with spectral analysis can be used to evaluate depth-dependent distribution of the mechanical properties based on the measurements of the surface deformation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.