Evidence map›Paper›PMID 25974031›Full record

ArticleMagnetic resonance in medicine2016

RF instrumentation for same-breath triple nuclear lung MR imaging of (1)H and hyperpolarized (3)He and (129)Xe at 1.5T.

Madhwesha Rao, Jim M Wild

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Functional Pulmonary Imaging.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. In vivo methods and applications of xenon-129 magnetic resonance.Progress in nuclear magnetic resonance spectroscopy · 2021
    Review
  6. Article
  7. Multiple breath washout of hyperpolarizedMagnetic resonance in medicine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Madhwesha RaoAcademic Unit of Radiology, University of Sheffield, Sheffield, United Kingdom.
Jim M WildAcademic Unit of Radiology, University of Sheffield, Sheffield, United Kingdom.

Funding

British Heart Foundation SP/14/6/31350Department of Health NIHR-RP-R3-12-027Medical Research Council MR/M008894/1
6 · The paper itself

Abstract

purposeThe hyperpolarized gases (3)He and (129)Xe have distinct properties and provide unique and complementary functional information from the lungs. A triple-nuclear, same-breath imaging examination of the lungs with (1)H, (3)He, and (129)Xe can therefore provide exclusive functional information from the gas images. In addition, the (1)H images provide complementary co-registered structural information in the same physiological time frame. The goal of this study was to design an RF system for triple nuclear lung MRI at 1.5T, consisting of a dual-tuned transceiver coil for (3)He and (129)Xe, RF switches and a nested (1)H receiver array.

methodsA dual-tuned transmit-receive dual-Helmholtz RF coil for (3)He and (129)Xe was designed and constructed to work in unison with a nested (1)H receiver array.

resultsTriple-nuclear imaging (structural and ventilation) and apparent diffusion coefficient mapping of the human lungs was performed in the same breath-hold using the integrated RF system. B1 maps and volumetric ventilation imaging using a three-dimensional, balanced steady-state free precession pulse sequence performed with both hyperpolarized (3)He and (129)Xe indicate good stand-alone performance of the coil for the respective nucleus.

conclusionTriple-nuclear same-breath lung imaging with a dual-tuned coil ((3)He and (129)Xe) and a nested (1)H array has been demonstrated with a custom RF system.

Indexed as

AdultBreath HoldingEquipment DesignHeliumHumansHydrogenLungMagnetic Resonance ImagingMaleXenon IsotopesHeliumHydrogenXenon Isotopesdual-tuned RF coilhyperpolarized gaslungspulmonarytriple nuclear imaging

Identifiers

PMID25974031
PMCPMC5427630

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.