ArticlePloS one2015
Neuropsychological Impairment in Prodromal, First-Episode, and Chronic Psychosis: Assessing RBANS Performance.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Advancing study of cognitive impairments for antipsychotic-naïve psychosis comparing high-income versus low- and middle-income countries with a focus on urban China: Systematic review of cognition and study methodology.Schizophrenia research · 2020Pooled it
- From the psychosis prodrome to the first-episode of psychosis: No evidence of a cognitive decline.Journal of psychiatric research · 2018Trial
- Dynamic, differentiated clinical trajectories and prediction in clinical high risk for psychosis.Molecular psychiatry · 2026Article
- High-Resolution Diffusion Tensor Imaging of the Cerebellum and Brainstem in Chiari Malformation Type I: Association with Function and Pain.Cerebellum (London, England) · 2026Article
- Divergent age-related cognitive impairments in first-episode psychosis.Schizophrenia research. Cognition · 2026Article
- Distribution of borderline personality disorder related impulsivity types in psychiatric clinical populations.BMC psychiatry · 2025Article
- Neurocognitive resilience as a predictor of psychosis onset and functional outcomes in individuals at high risk.BMC medicine · 2025Article
- Advancements and Future Directions in Prevention Based on Evaluation for Individuals With Clinical High Risk of Psychosis: Insights From the SHARP Study.Schizophrenia bulletin · 2025Review
- Cognitive Impairments in Drug-Naive Patients With First-Episode Negative Symptom-Dominant Psychosis.JAMA network open · 2024Article
- Duration of Untreated Prodromal Psychosis and Cognitive Impairments.JAMA network open · 2024Article
- Patterns of Impaired Neurocognitive Performance on the Global Neuropsychological Assessment, and Their Brain Structural Correlates in Recent-onset and Chronic Schizophrenia.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023Article
- Functional connectivity abnormalities in Type I Chiari: associations with cognition and pain.Brain communications · 2021Article
- Increased peripheral inflammation in schizophrenia is associated with worse cognitive performance and related cortical thickness reductions.European archives of psychiatry and clinical neuroscience · 2021Article
- Neurocognitive Impairment in Severe Mental Illness. Comparative study with Spanish Speaking Patients.Brain sciences · 2021Article
- Comparing the Self-Reported Personality Disorder Traits and Childhood Traumatic Experiences Between Patients With Schizophrenia Vs. Major Depressive Disorder.Frontiers in psychiatry · 2021Article
- Psychiatric, cognitive functioning and socio-cultural views of menstrual psychosis in Oman: an idiographic approach.BMC women's health · 2020Article
- Verbal memory measurement towards digital perspectives in first-episode psychosis: A review.Schizophrenia research. Cognition · 2020Review
- Global and Specific Profiles of Executive Functioning in Prodromal and Early Psychosis.Frontiers in psychiatry · 2019Article
- Diverse definitions of the early course of schizophrenia-a targeted literature review.NPJ schizophrenia · 2018Review
- A comparison of conversion rates, clinical profiles and predictors of outcomes in two independent samples of individuals at clinical high risk for psychosis in China.Schizophrenia research · 2018Article
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Authors and funding
19 authors.
Funding
Abstract
backgroundCognitive deficits are observed throughout all developmental phases of psychosis. However, prior studies have usually focused on a limited illness period and used a wide variety of cognitive instruments. Therefore, it has been difficult to characterize or highlight cognitive functioning in different stages of psychosis.
methodWe administered the RBANS (Repeatable Battery for the Assessment of Neuropsychological Status) tests to 4 participant subgroups, including healthy volunteers (controls, HC, n = 28), subjects at high risk for clinical psychosis (prodrome, CHR, n = 27), first-episode schizophrenia patients (FE-Sz, n = 26), and mid-term and long-term chronic schizophrenia patients (Ch-Sz, n =147). Comparison, correlation, and regression analyses of RBANS index scores were assessed among groups. We examined clinical outcomes over 2 years between the CHR and HC subjects, and RBANS domains were used as possible predictors for conversion to psychosis.
resultsPerformance on all RBANS domains was significantly impaired during a post-onset stage of psychosis (FE-Sz and Ch-Sz), and RBANS scores declined along with disease progression. Regression analyses showed that for CHR and HC subjects, baseline impairment in delayed memory (DM) significantly predicted conversion to psychosis. Additionally, partial correlations showed that for FE-Sz and Ch-Sz subjects, DM was the only correlate with a later stage of psychosis.
conclusionsCognitive deficits broadly emerged, and diminished functioning followed along with disease progression. Impairment in DM is perhaps one domain that helps us understand the development of psychosis. A critical need is to monitor and treat memory functioning for psychotic patients throughout all phases of the disease.
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