ReviewInternational journal for parasitology. Parasites and wildlife2015
A review of neosporosis and pathologic findings of Neospora caninum infection in wildlife.
Review in International journal for parasitology. Parasites and wildlife, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed, 3 syntheses or guidelines pooled it, 220 citations in OpenAlex.
- Global Prevalence of Neospora caninum in Domestic Pigs (Sus domesticus) and Wild Boars (Sus scrofa): A Systematic Review and Meta-Analysis.Veterinary medicine and science · 2025Pooled it
- Global prevalence of Neospora caninum in rodents: A systematic review and meta-analysis.Veterinary medicine and science · 2023Pooled it
- Systematic Review and Meta-analysis of Role of Felids as Intermediate Hosts in the Life Cycle of Neospora caninum Based on Serological Data.Acta parasitologica · 2023Pooled it
- Climate-Sensitive Redistribution of Veterinary Parasites: An Attribution Framework for One Health Surveillance and Control.Biology · 2026Review
- Seropositivity and Risk Factors forAnimals : an open access journal from MDPI · 2026Article
- First molecular identification and phylogenetic analysis ofJournal of veterinary research · 2026Article
- Neospora caninum Infection in Marine Mammals Stranding in Northeastern Pacific Ocean Region.Emerging infectious diseases · 2026Article
- Animal Tissue Mineralization: An Overview of Disease Processes, Comparative Pathology, and Diagnostic Approaches.Biomolecules · 2026Review
- Molecular Diagnosis and Quantification of Bovine Abortion Caused byVeterinary medicine international · 2026Article
- Infectious causes of pregnancy loss in cattle: a review of loss intensity and major reproductive pathogens involved.Animal reproduction · 2026Review
- In silico design of novel multi-epitope peptide vaccine against Neospora caninum induced cattle abortion targeting extracellular GRA2 and Nc-p43 protein.Scientific reports · 2025Article
- Molecular investigation of Neospora caninum in cattle in the Khomas region of Namibia.The Onderstepoort journal of veterinary research · 2025Article
- Intracellular Parasitic Infections Caused byVaccines · 2025Review
- Recent advances in nanogels in veterinary medicine.Veterinary research · 2025Review
- Article
- Successful Management of Presumed Reactivation of Neospora caninum Following Immunosuppression for Immune Thrombocytopenia in an Adult Doberman.Veterinary medicine and science · 2025Article
- GRA12 is a common virulence factor across Toxoplasma gondii strains and mouse subspecies.Nature communications · 2025Article
- Review of neosporosis: Disease insights and control approaches.Open veterinary journal · 2025Review
- Article
- High Exposure to Livestock Pathogens in Southern Pudu (Animals : an open access journal from MDPI · 2024Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neospora caninum is an apicomplexan parasite that is the etiologic agent of neosporosis, a devastating infectious disease regarded as a major cause of reproductive loss in cattle and neuromuscular disease in dogs worldwide. This protozoan pathogen is maintained in the environment by a heteroxenous life cycle that involves a definitive canid host and a wide range of intermediate hosts. In recent years, a number of wildlife species have been investigated for their possible involvement in the N. caninum life cycle and many have been implicated as intermediate hosts. However, in many instances these studies have utilized serological and molecular techniques to detect infection in clinically normal animals, and investigation of possible associated morbidity, mortality, and pathology has been neglected. As such, the occurrence and importance of Neospora-associated disease in wildlife species are unknown. In order to improve our understanding of the significance of N. caninum infection in nondomestic species, the present review provides an up-to-date summary of clinical neosporosis and N. caninum-associated pathologic lesions in naturally and experimentally infected wildlife species. We provide a list of all free-ranging and captive wildlife species identified with N. caninum infection to date using currently available diagnostic tools. The advantages and disadvantages of diagnostic methods in wildlife are addressed in order to recommend optimal diagnosis of confirming N. caninum infection and neosporosis in nondomestic species. Although current data would suggest that N. caninum infection does not adversely impact wildlife populations, there is a need for greater international uniformity in the diagnosis of N. caninum infection and neosporosis in nondomestic species in order to assess the true consequences of parasite infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.