Evidence map›Paper›PMID 25973075›Full record

ReviewInternational journal of clinical and experimental pathology2015

Crescentic acute glomerulonephritis with isolated C3 deposition: a case report and review of literature.

Song Mao, Xiaoyan Xuan, Yugen Sha, Sanlong Zhao, Aihua Zhang, Songming Huang

Open access · greenAbstract readCase ReportsReview
In one paragraph

Review in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Angiotensin II and post-streptococcal glomerulonephritis.Clinical and experimental nephrology · 2024
    Review
  2. Lupus nephritis or not? A simple and clinically friendly machine learning pipeline to help diagnosis of lupus nephritis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
  3. Case reports in nephrology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Song MaoDepartment of Nephrology, Nanjing Children's Hospital, Affiliated to Nanjing Medical University Nanjing, China.
Xiaoyan XuanDepartment of Nephrology, Nanjing Children's Hospital, Affiliated to Nanjing Medical University Nanjing, China.
Yugen ShaDepartment of Nephrology, Nanjing Children's Hospital, Affiliated to Nanjing Medical University Nanjing, China.
Sanlong ZhaoDepartment of Nephrology, Nanjing Children's Hospital, Affiliated to Nanjing Medical University Nanjing, China.
Aihua ZhangDepartment of Nephrology, Nanjing Children's Hospital, Affiliated to Nanjing Medical University Nanjing, China.
Songming HuangDepartment of Nephrology, Nanjing Children's Hospital, Affiliated to Nanjing Medical University Nanjing, China.
Nanjing Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An eight-year-old girl, presenting with palpebral edema, gross hematuria, and foam in urine, was admitted to our hospital. Investigations indicated increased serum antistreptolysin O (ASO) and anti-mycoplasma antibody titers. Renal biopsy showed crescentic poststreptococcal acute glomerulonephritis (CPAGN) with isolated C3 deposition in the glomeruli. Electro-microscope examination showed subepithelial deposition of electron dense material. She received the double pulse therapies of methylprednisolone and cyclophosphamide as well as the treatment of oral prednisolone, angiotensin converting enzyme-II (ACE-II) inhibitor, dipyridamole and traditional Chinese medicine. The complete clinical remission was achieved after 9 months. No serious adverse effects were observed during the follow-up. Our findings indicated that CPAGN with isolated C3 deposition might have a favorable prognosis after aggressive immunosuppressive treatment. However, the influence of isolated C3 deposition on CPAGN prognosis remains to be clarified.

Indexed as

Acute DiseaseAngiotensin-Converting Enzyme InhibitorsBiomarkersBiopsyChildComplement C3Drug Therapy, CombinationFemaleFluorescent Antibody TechniqueGlomerulonephritisHumansImmunosuppressive AgentsKidney GlomerulusMicroscopy, ElectronRemission InductionStreptococcal InfectionsAngiotensin-Converting Enzyme InhibitorsBiomarkersC3 protein, humanComplement C3Immunosuppressive AgentsC3Crescentic poststreptococcal acute glomerulonephritisdeposition

Identifiers

PMID25973075
PMCPMC4396300
OpenAlexW2410794225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.